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Found 98 with Last Name = 'reynolds' and Initial = 't'
TargetActivin receptor type-1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  8nM Kd:  25nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610092(CHEMBL5276395)
Affinity DataIC50:  34nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610074(CHEMBL5280465)
Affinity DataIC50:  45nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610092(CHEMBL5276395)
Affinity DataIC50:  48nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610089(CHEMBL5277312)
Affinity DataIC50:  56nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610091(CHEMBL5289895)
Affinity DataIC50:  57nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610090(CHEMBL5286973)
Affinity DataIC50:  86nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  107nM Kd:  19nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610066(CHEMBL5284462)
Affinity DataIC50:  184nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  205nM Kd:  670nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610067(CHEMBL5272337)
Affinity DataIC50:  229nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610087(CHEMBL5290423)
Affinity DataIC50:  243nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610079(CHEMBL5267805)
Affinity DataIC50:  250nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610081(CHEMBL5273850)
Affinity DataIC50:  250nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610085(CHEMBL5288026)
Affinity DataIC50:  255nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610083(CHEMBL5274479)
Affinity DataIC50:  256nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610095(CHEMBL5275106)
Affinity DataIC50:  260nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610088(CHEMBL5288385)
Affinity DataIC50:  278nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610082(CHEMBL5283046)
Affinity DataIC50:  279nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610089(CHEMBL5277312)
Affinity DataIC50:  328nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610080(CHEMBL5281407)
Affinity DataIC50:  330nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610094(CHEMBL5286309)
Affinity DataIC50:  343nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610084(CHEMBL5281828)
Affinity DataIC50:  381nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)
Affinity DataIC50:  405nM Kd:  1.00E+3nMAssay Description:Biochemical binding assays (DiscoveRx) and in vitro enzyme inhibition assays (LanthaScreen, Life Technologies) were conducted to determine the bindin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610074(CHEMBL5280465)
Affinity DataIC50:  426nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610071(CHEMBL5273536)
Affinity DataIC50:  447nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610063(CHEMBL5277885)
Affinity DataIC50:  478nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610065(CHEMBL5271250)
Affinity DataIC50:  480nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610056(CHEMBL5269682)
Affinity DataIC50:  510nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610090(CHEMBL5286973)
Affinity DataIC50:  563nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610070(CHEMBL5279505)
Affinity DataIC50:  596nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610091(CHEMBL5289895)
Affinity DataIC50:  639nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610096(CHEMBL5276326)
Affinity DataIC50:  650nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610086(CHEMBL5279420)
Affinity DataIC50:  726nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610097(CHEMBL5273198)
Affinity DataIC50:  840nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610093(CHEMBL5279033)
Affinity DataIC50:  861nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610067(CHEMBL5272337)
Affinity DataIC50:  2.07E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610088(CHEMBL5288385)
Affinity DataIC50:  2.12E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610073(CHEMBL5272363)
Affinity DataIC50:  2.22E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610066(CHEMBL5284462)
Affinity DataIC50:  2.40E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610072(CHEMBL5277792)
Affinity DataIC50:  2.49E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610083(CHEMBL5274479)
Affinity DataIC50:  2.55E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610057(CHEMBL5284971)
Affinity DataIC50:  2.74E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610082(CHEMBL5283046)
Affinity DataIC50:  2.74E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610078(CHEMBL5270073)
Affinity DataIC50:  3.03E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610079(CHEMBL5267805)
Affinity DataIC50:  3.67E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610075(CHEMBL5267711)
Affinity DataIC50:  3.71E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50610081(CHEMBL5273850)
Affinity DataIC50:  3.79E+3nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610077(CHEMBL5276392)
Affinity DataIC50:  3.84E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50610076(CHEMBL5270730)
Affinity DataIC50:  3.87E+3nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
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