Affinity DataIC50: 5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells using human recombinant SHH assessed as effect on SMO/SHH transient transcriptional activation after 20 hr...More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetMembrane-bound transcription factor site-1 protease(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human S1P expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair