Compile Data Set for Download or QSAR
maximum 50k data
Found 69 with Last Name = 'roberts' and Initial = 'gc'
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.00400nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50225252(CHEMBL296525)
Affinity DataKi: <0.0100nMAssay Description:Inhibition constant of compound against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027975(5-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.200nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027973(6-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.400nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027972(7-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.600nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027971(4-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027977(2-{3-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)...)
Affinity DataKi:  1.70nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027976(CHEMBL45202 | {3-[2-Bromo-5-(2,4-diamino-pyrimidin...)
Affinity DataKi:  4.10nMAssay Description:Inhibition constant of compound against L. casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027974(3-{3-[2-Bromo-5-(2,4-diamino-pyrimidin-5-ylmethyl)...)
Affinity DataKi:  5.30nMAssay Description:Inhibition constant of compound against L. casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50027970(5-(4-Bromo-3,5-dimethoxy-benzyl)-pyrimidine-2,4-di...)
Affinity DataKi:  11nMAssay Description:Inhibition constant of compound against L. casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataKi:  30nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  180nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataKi:  7.50E+3nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50370411(CINCHORINE | GNF-PF-3189)
Affinity DataKi:  2.10E+4nMAssay Description:Binding affinity for cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataIC50:  8.40nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004495(CHEMBL101015 | Hexadecanoic acid 3-[hydroxy-(2-hyd...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004502(CHEMBL101972 | Phosphoric acid 2-hexadecanoylamino...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004499((R)-O-(2-Hexadecanamidoisohexyl) phosphocholine | ...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004504((R)-O-(2-Hexadecanamidopropyl] phosphocholine | CH...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50066721(1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154453(1-(4-Fluoro-phenyl)-4-{4-[(4-fluoro-phenyl)-hydrox...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50370411(CINCHORINE | GNF-PF-3189)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154467(1-[3-(2,5-Dichloro-phenylsulfanyl)-propyl]-piperaz...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154454((3-Aminomethyl-7-chloro-quinolin-4-yl)-butyl-amine...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154460(3-(9-Methoxy-5,11-dimethyl-pyrido[4,3-b]carbazol-6...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004502(CHEMBL101972 | Phosphoric acid 2-hexadecanoylamino...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154461(2-[1-(2-Chloro-benzyl)-2-methyl-5-methylsulfanyl-1...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004495(CHEMBL101015 | Hexadecanoic acid 3-[hydroxy-(2-hyd...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154461(2-[1-(2-Chloro-benzyl)-2-methyl-5-methylsulfanyl-1...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004493(CHEMBL101890 | O-(2-hexadecanamidoethyl) phosphoch...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004505((S)-O-(2-Hexadecanamidoisohexyl) phosphocholine | ...)
Affinity DataIC50:  4.50E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004500(CHEMBL319067 | Phosphoric acid mono-(2-hexadecanoy...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004501((E)-(R)-O-(2-Dec-3-enamidoisohexyl) phosphocholine...)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154459(CHEMBL189830 | NCI-180973 | {2-[4-((E)-1,2-Dipheny...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50014779(1-[Bis-(4-chloro-phenyl)-methyl]-piperazine | CHEM...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154452(1-Amino-3-(4-chloro-benzylsulfanyl)-propan-2-ol | ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004498(CHEMBL99161 | O-[2-(2-Naphthalenecarboxamido)ethyl...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154468(2-(2-Amino-ethyl)-3-(4-chloro-phenyl)-3-hydroxy-2,...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154469(CHEMBL188797 | Diethyl-{2-[2-(4-oxo-2-phenyl-4H-ch...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004496(CHEMBL318193 | Phosphoric acid mono-(2-hexadecanoy...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50022673((5-(3,4-dichlorophenyl)-2,3-dihydro-1H-pyrrolizine...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004497(CHEMBL330205 | Phosphoric acid 2-trimethylamino-et...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154462(CHEMBL188427 | N-Methyl-N-[4-(7-methyl-1H-imidazo[...)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50154449(5-[4-(2-Amino-ethylamino)-3-nitro-phenyl]-6-ethyl-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Fisons

Curated by ChEMBL
LigandPNGBDBM50004499((R)-O-(2-Hexadecanamidoisohexyl) phosphocholine | ...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50033894(5-Amino-2-(2-dimethylamino-ethyl)-benzo[de]isoquin...)
Affinity DataIC50:  3.96E+4nMAssay Description:Inhibitory concentration against cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 69 total ) | Next | Last >>
Jump to: