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Found 3004 with Last Name = 'roberts' and Initial = 'j'
TargetBromodomain-containing protein 3 [306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.00270nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [333-460](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.00430nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.00690nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.00780nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [71-194,348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.0100nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3 [24-144,306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0120nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-168,333-460](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.0120nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [71-194](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.0140nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [71-194,348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0240nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0330nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM412656(US10399974, Example 54)
Affinity DataKi:  0.0470nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [333-460](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0530nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3 [24-144](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0590nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0620nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein [251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.0660nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3 [306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0700nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein [21-137,251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0760nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241208(US11046688, Example 50 | US9409907, 50)
Affinity DataKi:  0.0840nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein [251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0860nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-168,333-460](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0870nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50464039(CHEMBL4245639)
Affinity DataKi:  0.0880nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241333(US10479788, Example 177 | US11046688, Example 177 ...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-168](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0990nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241338(US10479788, Example 182 | US11046688, Example 182 ...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM412611(N-(2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phen...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3 [24-144,306-416](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.110nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM412614(N2-(4-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)-2-ethox...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50464037(CHEMBL4240502)
Affinity DataKi:  0.120nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3 [24-144](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.130nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241335(US9409907, 179)
Affinity DataKi:  0.130nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [71-194](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.160nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4 [44-168](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.180nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50464040(CHEMBL4251352)
Affinity DataKi:  0.190nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241235(US10479788, Example 77 | US11046688, Example 77 | ...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM412610(1-(2-((2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein [21-137](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.290nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50464038(CHEMBL4250961)
Affinity DataKi:  0.380nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain testis-specific protein [21-137,251-382](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.420nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241226(US10479788, Example 68 | US11046688, Example 68 | ...)
Affinity DataKi:  0.440nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241226(US10479788, Example 68 | US11046688, Example 68 | ...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain testis-specific protein [21-137](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.560nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50225074((1S,3S,5S)-2-[(S)-2-amino-2-(3-hydroxy-adamantan-1...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM11542((1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1...)
Affinity DataKi:  0.600nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
TargetGlutamate receptor(RABBIT)
University of Bristol

Curated by PDSP Ki Database
LigandPNGBDBM50252103((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...)
Affinity DataKi:  0.710nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM241207(US11046688, Example 49 | US9409907, 49)
Affinity DataKi:  0.780nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM412658(US10399974, Example 56)
Affinity DataKi:  0.820nMAssay Description:Inhibition of full length human N-terminal 6xHis-tagged MPS1 expressed in baculovirus expression system using 5FAM-H236 peptide as substrate after 60...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM11541((1S,3S,5S)-2-[(2S)-2-(adamantan-1-yl)-2-aminoacety...)
Affinity DataKi:  0.900nM ΔG°:  -51.1kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26277(N-(3,5-difluorophenyl)-2-{3-[(7-{3-[4-(hydroxymeth...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26288(N-(2,3-difluorophenyl)-2-{3-[(7-{3-[4-(2-hydroxyet...)
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26302(N-(3-fluorophenyl)-2-{3-[(7-{3-[(2R)-2-(hydroxymet...)
Affinity DataKi: <1nM ΔG°: <-51.4kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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