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Found 67 with Last Name = 'rodriguez' and Initial = 'h'
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM10044((2S,15S)-15-methyl-2-[(methylsulfanyl)methyl]tetra...)
Affinity DataKi:  1nMAssay Description:Aromatase inhibitor potency as iron-binding-related type II difference spectrumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  470nMAssay Description:Competitive inhibition of human placental Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  0.0300nMAssay Description:Aromatase inhibitor potency as iron-binding-related type II difference spectrumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368174(CHEMBL1203762)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  6.40nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368173(CHEMBL1203766)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008725(4-(6,7,8,9-Tetrahydro-5H-imidazo[1,5-a]azepin-5-yl...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008726(CHEMBL348913 | [4-(5,6,7,8-Tetrahydro-imidazo[1,5-...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008733(1-(4-Cyanobenzyl)-1H-imidazole | 4-((1H-imidazol-1...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008729(1-(4-Cyanobenzyl)-5-methyl-1H-imidazole | 4-(5-Met...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368172(CHEMBL1203757)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50368175(CHEMBL1203760)
Affinity DataIC50:  21nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  39nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348420(CHEMBL1800951)
Affinity DataIC50:  60nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348418(CHEMBL1800931)
Affinity DataIC50:  80nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008724(4-(5,6,7,8-Tetrahydro-imidazo[1,5-a]pyridin-5-yl)-...)
Affinity DataIC50:  93nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50008730(4-(5,6,7,8-Tetrahydro-imidazo[1,5-a]pyridin-5-yl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ACTH-stimulated aldosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348421(CHEMBL1800953)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348422(CHEMBL1800954)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348423(CHEMBL1800955)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348424(CHEMBL1800952)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50348419(CHEMBL1800933)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28356((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....)
Affinity DataIC50:  1.15E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28356((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataIC50:  2.18E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28346(1-[(9S)-6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pent...)
Affinity DataIC50:  2.91E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibition of cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28341((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...)
Affinity DataIC50:  3.19E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28341((9aR)-2-[3-(2-chloro-10H-phenothiazin-10-yl)-3-oxo...)
Affinity DataIC50:  3.54E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28346(1-[(9S)-6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pent...)
Affinity DataIC50:  3.60E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28357(ZINC00347760, 26 | {3-[(10S)-2,9-dithiatricyclo[9....)
Affinity DataIC50:  3.67E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28357(ZINC00347760, 26 | {3-[(10S)-2,9-dithiatricyclo[9....)
Affinity DataIC50:  3.73E+4nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28359(1-benzyl-4-[(E)-[(1-cyclohexyl-2,4,6-trioxo-1,3-di...)
Affinity DataIC50:  4.52E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28349(N-methyl-N-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...)
Affinity DataIC50:  4.69E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28347(3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2....)
Affinity DataIC50:  5.43E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28349(N-methyl-N-({[2-(phenylsulfanyl)phenyl]carbamoyl}m...)
Affinity DataIC50:  5.63E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28358((2R,7S)-18-chloro-3,3-dimethyl-14-thia-3-azatetrac...)
Affinity DataIC50:  5.87E+4nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28358((2R,7S)-18-chloro-3,3-dimethyl-14-thia-3-azatetrac...)
Affinity DataIC50:  7.53E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28345(1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]...)
Affinity DataIC50:  7.87E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  8.00E+4nMAssay Description:In vitro inhibition of progesterone production in hamster ovarian tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28354(2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...)
Affinity DataIC50:  8.44E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28355((2S)-2-benzenesulfonamido-N-[2-(phenylsulfanyl)phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28359(1-benzyl-4-[(E)-[(1-cyclohexyl-2,4,6-trioxo-1,3-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28360(4-[(4S)-4-[(3-chlorophenyl)carbamoyl]-6-oxo-1,4,5,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of ACTH-stimulated corticosterone production in rat adrenal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28354(2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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