Affinity DataKi: 3.30nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 199nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 271nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
Affinity DataKi: 997nMAssay Description:Inhibition of human recombinant microsomal MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 min...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Dart Neuroscience
Curated by ChEMBL
Dart Neuroscience
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MAO-B in rat whole brain homogenate in presence of clorgylineMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Dart Neuroscience
Curated by ChEMBL
Dart Neuroscience
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of MAO-A in rat whole brain homogenate in presence of selegilineMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determinedMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.150.47 uMMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.431.12 uMMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.461.81 uMMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.431.85 uMMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.811.70 uMMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Universidad De Valencia
Curated by ChEMBL
Universidad De Valencia
Curated by ChEMBL
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibitory concentration of the compound required to produce 50% inhibition of the response was determined; range-0.541.16 uMMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of GGPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human FPPS after 10 mins using [14C]IPP as substrate by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKd: 59nMAssay Description:Binding affinity to human recombinant microsomal MAO-B by ITCMore data for this Ligand-Target Pair
Affinity DataKd: 187nMAssay Description:Binding affinity to human recombinant microsomal MAO-B by ITCMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+4nMAssay Description:Inhibition of human recombinant soluble MAO-B assessed as thermal shift after 20 mins by SYPRO orange staining-based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.10E+3nMAssay Description:Inhibition of human recombinant soluble MAO-B assessed as thermal shift after 20 mins by SYPRO orange staining-based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+4nMAssay Description:Inhibition of human recombinant soluble MAO-B assessed as thermal shift after 20 mins by SYPRO orange staining-based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 66nMAssay Description:Binding affinity to human recombinant microsomal MAO-B by ITCMore data for this Ligand-Target Pair
Affinity DataKd: 275nMAssay Description:Binding affinity to human recombinant microsomal MAO-B by ITCMore data for this Ligand-Target Pair