TargetDimer of Gag-Pol polyprotein [489-587,V571I](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 0.0520nM ΔG°: -59.7kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,L565M](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 0.114nM ΔG°: -57.7kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,I539L](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 0.323nM ΔG°: -55.1kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 0.358nM ΔG°: -54.8kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,L512I](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 0.585nM ΔG°: -53.6kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,V521I](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 2.64nM ΔG°: -49.8kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,L512V](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 2.81nM ΔG°: -49.6kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,I573V](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 3.11nM ΔG°: -49.4kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [514-612](Human immunodeficiency virus type 2)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 3.32nM ΔG°: -49.2kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,I536L](Human immunodeficiency virus type 1)
Merck Research Laboratories
Merck Research Laboratories
Affinity DataKi: 6.62nM ΔG°: -47.5kJ/molepH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
Affinity DataKi: 3.09E+4nMAssay Description:Non-competitive inhibition of recombinant human MIF assessed as inhibition constant using varying levels of p-hydroxyphenylpyruvate as substrate by L...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMpH: 7.2Assay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 0.910nMpH: 7.2Assay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMpH: 7.2Assay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Concentration of the compound required in vitro to inhibit Matrix metalloproteinase-13More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloproteinase 13 (MMP-13).More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.2Assay Description:The assay is a capture of radioactive 33P phosphorylated product through filtration. The interactions of BTK, biotinylated SH2 peptide substrate (Src...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloproteinase-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against matrix metalloproteinase 9 (MMP-9).More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair