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Found 157 with Last Name = 'santini' and Initial = 'am'
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143361((S)-N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-heptane-1,...)
Affinity DataIC50:  9nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143364(CHEMBL57657 | N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-...)
Affinity DataIC50:  18nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50080153((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)
Affinity DataIC50:  27nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266796(CHEMBL4068580)
Affinity DataIC50:  34nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266838(CHEMBL4084982)
Affinity DataIC50:  35nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143345(CHEMBL57487 | N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-...)
Affinity DataIC50:  38nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143358((S)-N*1*,N*1*-Diethyl-N*4*-(1,2,3,4,5,6,7,8-octahy...)
Affinity DataIC50:  43nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266824(CHEMBL4082808)
Affinity DataIC50:  43nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266783(CHEMBL4086010)
Affinity DataIC50:  50nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143348(CHEMBL299461 | N*1*-Acridin-9-yl-1-cyclopropyl-N*4...)
Affinity DataIC50:  52nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266784(CHEMBL4103928)
Affinity DataIC50:  53nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266789(CHEMBL4088453)
Affinity DataIC50:  56nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266823(CHEMBL4097435)
Affinity DataIC50:  58nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266788(CHEMBL4067192)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266811(CHEMBL4059919)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266838(CHEMBL4084982)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266788(CHEMBL4067192)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266811(CHEMBL4059919)
Affinity DataIC50:  62nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50:  66nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266840(CHEMBL4089707 | US11072585, Example 56)
Affinity DataIC50:  67nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266786(CHEMBL4063337)
Affinity DataIC50:  74nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266837(CHEMBL4100783)
Affinity DataIC50:  77nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266822(CHEMBL4079398)
Affinity DataIC50:  78nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266824(CHEMBL4082808)
Affinity DataIC50:  80nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266795(CHEMBL4063420)
Affinity DataIC50:  81nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266795(CHEMBL4063420)
Affinity DataIC50:  81nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266787(CHEMBL4092740)
Affinity DataIC50:  82nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50:  83nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266837(CHEMBL4100783)
Affinity DataIC50:  88nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266826(CHEMBL4105137)
Affinity DataIC50:  96nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266823(CHEMBL4097435)
Affinity DataIC50:  100nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266796(CHEMBL4068580)
Affinity DataIC50:  100nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266823(CHEMBL4097435)
Affinity DataIC50:  100nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266822(CHEMBL4079398)
Affinity DataIC50:  100nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Mus musculus)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266786(CHEMBL4063337)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant mouse LOXL2 expressed in mouse whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266786(CHEMBL4063337)
Affinity DataIC50:  110nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143357((S)-N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-pentane-1,...)
Affinity DataIC50:  110nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266839(CHEMBL4071963)
Affinity DataIC50:  110nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266794(CHEMBL4093765)
Affinity DataIC50:  110nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Rattus norvegicus)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266786(CHEMBL4063337)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266785(CHEMBL4066192 | US11358936, Compound 1-41)
Affinity DataIC50:  120nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266783(CHEMBL4086010)
Affinity DataIC50:  130nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266783(CHEMBL4086010)
Affinity DataIC50:  130nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266789(CHEMBL4088453)
Affinity DataIC50:  130nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266821(CHEMBL4087273 | US11072585, Example 34)
Affinity DataIC50:  130nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266826(CHEMBL4105137)
Affinity DataIC50:  140nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266839(CHEMBL4071963)
Affinity DataIC50:  150nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266821(CHEMBL4087273 | US11072585, Example 34)
Affinity DataIC50:  160nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143347(CHEMBL58047 | N*1*,N*1*-Diethyl-N*4*-(1,2,3,4,5,6,...)
Affinity DataIC50:  160nMAssay Description:Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266825(CHEMBL4085053)
Affinity DataIC50:  180nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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