TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Competitive inhibition of Caulobacter vibrioides full length wild type cell cycle histidine kinase CckA deltaTM Escherichia coli BL21-AI in presence ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 2.10E+4nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 3.41E+4nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 4.52E+4nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 4.93E+4nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.12E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.16E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.35E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.59E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 2.97E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 3.63E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 4.62E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 4.78E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 5.84E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 6.14E+5nMAssay Description:Inhibition of SARS coronavirus 3CL protease pretreated for 10 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human BACE1 using (7-methoxycoumarin-4-yl)acetyl-SEVNL*DAEFRK(2,4-dinitrophenyl)-RR-NH2) as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of recombinant human BACE1 using (7-methoxycoumarin-4-yl)acetyl-SEVNL*DAEFRK(2,4-dinitrophenyl)-RR-NH2) as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Inhibition of recombinant human BACE1 using (7-methoxycoumarin-4-yl)acetyl-SEVNL*DAEFRK(2,4-dinitrophenyl)-RR-NH2) as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant Arg235 region of BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
TargetPhosphate regulon sensor protein PhoR(Escherichia coli (strain K12))
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Escherichia coli DHp-catalytic domain PhoR autophosphorylation expressed in Escherichia coli RIL in presence of gamma-32P-ATP by SDS-PA...More data for this Ligand-Target Pair
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
TargetSensor protein kinase WalK(Staphylococcus epidermidis (strain ATCC 35984 / RP...)
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant Staphylococcus epidermidis ATCC 35984 N-terminal GB1-tagged YycG expressed in Escherichia coli BL21 (DE3) preincubated for ...More data for this Ligand-Target Pair
TargetSensor protein kinase WalK(Staphylococcus epidermidis (strain ATCC 35984 / RP...)
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant Staphylococcus epidermidis ATCC 35984 N-terminal GB1-tagged YycG expressed in Escherichia coli BL21 (DE3) preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 5.69E+4nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae VicK preincubated for 30 mins followed by [gamma-33P]ATP addition after 30 mins by SDS-PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of Escherichia coli CheA preincubated for 30 mins followed by [gamma-33P]ATP addition after 30 mins by SDS-PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+5nMAssay Description:Inhibition of recombinant Caulobacter vibrioides cell cycle histidine kinase CckA deltaTM mutant DHp domain (70 to 691 residues) expressed in Escheri...More data for this Ligand-Target Pair
TargetSensor protein kinase WalK(Staphylococcus aureus subsp. aureus CN1)
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of Staphylococcus aureus DHp-catalytic domain PhoR autophosphorylation expressed in Escherichia coli RIL in presence of gamma-32P-ATP by S...More data for this Ligand-Target Pair
Affinity DataIC50: 2.16E+5nMAssay Description:Inhibition of Streptococcus pneumoniae VicK preincubated for 30 mins followed by [gamma-33P]ATP addition after 30 mins by SDS-PAGE methodMore data for this Ligand-Target Pair
TargetVirulence sensor histidine kinase PhoQ(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 2.38E+5nMAssay Description:Inhibition of recombinant Salmonella typhimurium N-terminal His6-SUMO-tagged DHp-catalytic domain PhoQ (257 to 487 residues) autophosphorylation expr...More data for this Ligand-Target Pair
TargetVirulence sensor histidine kinase PhoQ(Salmonella typhimurium (strain LT2 / SGSC1412 / AT...)
Williams College
Curated by ChEMBL
Williams College
Curated by ChEMBL
Affinity DataIC50: 2.61E+5nMAssay Description:Inhibition of recombinant Salmonella typhimurium N-terminal His6-SUMO-tagged DHp-catalytic domain PhoQ (257 to 487 residues) autophosphorylation expr...More data for this Ligand-Target Pair