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Found 218 with Last Name = 'schaefer' and Initial = 'vg'
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19387(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181184(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((3-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181180(CHEMBL377514 | N-(3,5-dimethylbenzyl)-3-(5-(4-(4-(...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181214(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((4-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181184(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((3-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158330((+/-)isobutyl 8-chloro-2-((4-(diethylamino)phenyl)...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to GHSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181191(CHEMBL205711 | N-(3-chlorobenzyl)-3-(5-(4-(4-(meth...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181217(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((me...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181182(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((fu...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181201(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(iso...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153531(3-(2,6-Dichloro-phenyl)-5-(2-[1,3]dioxan-2-yl-ethy...)
Affinity DataIC50:  3nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181180(CHEMBL377514 | N-(3,5-dimethylbenzyl)-3-(5-(4-(4-(...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181229(5-[4-(4-methanesulfonyl-benzylamino)-phenyl]-6-(5-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181225(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((be...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181192(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-octy...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181191(CHEMBL205711 | N-(3-chlorobenzyl)-3-(5-(4-(4-(meth...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181204(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isop...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181179(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((ph...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153534(3-(2,6-Dichloro-phenyl)-5-(2-[1,3]dioxan-2-yl-ethy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of binding to human growth hormone secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181176(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-hept...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181181(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-hexy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153534(3-(2,6-Dichloro-phenyl)-5-(2-[1,3]dioxan-2-yl-ethy...)
Affinity DataIC50:  6nMAssay Description:Ability to displace [125I]-ghrelin from cloned human GHS-R expressed in CHO-K cells was determined (Kd of ghrelin is 0.4 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181201(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(iso...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153528(5-(2-Benzo[1,3]dioxol-5-yl-ethyl)-3-(2,6-dichloro-...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against mouse Growth hormone secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19387(2,4-diaminopyrimidine derivative, 8c | 6-[(benzylo...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181185(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(met...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153547(3-(2,6-Dichloro-phenyl)-5-[2-(2-oxo-piperidin-1-yl...)
Affinity DataIC50:  8nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153547(3-(2,6-Dichloro-phenyl)-5-[2-(2-oxo-piperidin-1-yl...)
Affinity DataIC50:  9nMAssay Description:Ability to displace [125I]-ghrelin from cloned human GHS-R expressed in CHO-K cells was determined (Kd of ghrelin is 0.4 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181217(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((me...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50161052(3-(2,6-Dichloro-phenyl)-5-(2-[1,3]dioxan-2-yl-ethy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of binding to human growth hormone secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181179(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((ph...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181182(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((fu...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181229(5-[4-(4-methanesulfonyl-benzylamino)-phenyl]-6-(5-...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19351(2,4-diaminopyrimidine-based antagonist, 4c | 6-eth...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153545(3-(2,6-Dichloro-phenyl)-5-[2-(3-methyl-2-oxo-imida...)
Affinity DataIC50:  10nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50161052(3-(2,6-Dichloro-phenyl)-5-(2-[1,3]dioxan-2-yl-ethy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ghrelin-induced increase of intracellular [Ca2+] in CHO¿K cell FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181210(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(((4...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181193(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isob...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181206(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-buty...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181211(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-tert...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158329((+/-)-isobutyl 2-({[4-(diethylamino)phenyl]amino}c...)
Affinity DataIC50:  11nMAssay Description:Binding affinity to GHSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181214(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((4-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153528(5-(2-Benzo[1,3]dioxol-5-yl-ethyl)-3-(2,6-dichloro-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against rat Growth hormone secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181209(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-(ind...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181204(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-isop...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181188(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-cycl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human GHS receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153534(3-(2,6-Dichloro-phenyl)-5-(2-[1,3]dioxan-2-yl-ethy...)
Affinity DataIC50:  14nMAssay Description:Inhibition of ghrelin-induced increase of intracellular [Ca2+] in CHO¿K cell FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153536(3-(2,6-Dichloro-phenyl)-5-[2-(2,2-dimethyl-5-oxo-p...)
Affinity DataIC50:  15nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50181196(5-(4-(4-(methylsulfonyl)benzylamino)phenyl)-6-((cy...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human GHS receptor by binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50158327((+/-)isobutyl 2-((4-(diethylamino)phenyl)carbamoyl...)
Affinity DataIC50:  16nMAssay Description:Binding affinity to GHSRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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