Found 118 with Last Name = 'schiano-moriello' and Initial = 'a' TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity against human recombinant TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ influx pre-treated 5 m...More data for this Ligand-Target Pair
3D Structure (crystal)TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allylisothiocyanate-induced Ca2+ response preincubated for 5 min...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 680nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetHeat sensitive channel TRPV3(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity against rat recombinant TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced Ca2+ influx pre-treated 5 mins bef...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ response preincubated for 5 mins followed by LP...More data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.71E+3nMAssay Description:Antagonist activity against rat recombinant TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced Ca2+ influx pre-treated 5 mins bef...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.82E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.13E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.57E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced Ca2+ response preincubated for 5 mins followed by...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity against rat recombinant TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced Ca2+ influx pre-treated 5 mins bef...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced Ca2+ response preincubated for 5 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced Ca2+ response preincubated for 5 mins followed by...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Antagonist activity at rat TRPA1 expressed in HEK293 cells assessed as inhibition of allylisothiocyanate-induced Ca2+ response preincubated for 5 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 5.25E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 4(Rattus norvegicus)
University Of Naples Federico Ii
Curated by ChEMBL
University Of Naples Federico Ii
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK1016790A-induced Ca2+ response preincubated for 5 mins follow...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 9.12E+3nMAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMpH: 9.0 T: 2°CAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
