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Found 74 with Last Name = 'shahabi' and Initial = 'd'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613803(CHEMBL5291125)
Affinity DataKi:  0.600nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613809(CHEMBL5266228)
Affinity DataKi:  1.5nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613802(CHEMBL5287201)
Affinity DataKi:  4.40nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613808(CHEMBL5267260)
Affinity DataKi:  5.30nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613429(CHEMBL5271223)
Affinity DataKi:  8.90nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613806(CHEMBL5280093)
Affinity DataKi:  9.10nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50608624(CHEMBL5274743)
Affinity DataKi:  13nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  16nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496891(GRL-2420)
Affinity DataKi:  18nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613804(CHEMBL5287711)
Affinity DataKi:  92nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613810(CHEMBL5271083)
Affinity DataKi:  302nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613807(CHEMBL5288746)
Affinity DataKi:  388nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613813(CHEMBL5284706)
Affinity DataKi:  445nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613812(CHEMBL5268648)
Affinity DataKi:  1.78E+5nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613805(CHEMBL5281851)
Affinity DataKi:  3.10E+5nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)TBA
LigandPNGBDBM50613811(CHEMBL5278603)
Affinity DataKi:  3.37E+5nMAssay Description:Inhibition of HIV-1 protease using Abz-NF-6 as substrate assessed as inhibition constant measured every 2 mins for 20 mins by fluorescence based ELIS...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496875(indole chloropyridinyl-ester derived, 7d)
Affinity DataIC50:  73nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496873(indole chloropyridinyl-ester derived, 7b)
Affinity DataIC50:  120nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM429304(CVD-0006354 | acs.jmedchem.1c00409_ST.426 | indole...)
Affinity DataIC50:  250nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM429306(acs.jmedchem.1c00409_ST.427 | indole chloropyridin...)
Affinity DataIC50:  310nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496871(indole chloropyridinyl-ester derived, 2)
Affinity DataIC50:  320nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496881(indole chloropyridinyl-ester derived, 7j)
Affinity DataIC50:  340nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496876(indole chloropyridinyl-ester derived, 7e)
Affinity DataIC50:  380nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496884(indole chloropyridinyl-ester derived, 7m)
Affinity DataIC50:  419nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496877(indole chloropyridinyl-ester derived, 7f)
Affinity DataIC50:  470nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496882(indole chloropyridinyl-ester derived, 7k)
Affinity DataIC50:  489nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496879(indole chloropyridinyl-ester derived, 7h)
Affinity DataIC50:  590nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496880(indole chloropyridinyl-ester derived, 7i)
Affinity DataIC50:  870nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496874(indole chloropyridinyl-ester derived, 7c)
Affinity DataIC50:  900nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496883(indole chloropyridinyl-ester derived, 7l)
Affinity DataIC50:  1.19E+3nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496888(indole chloropyridinyl-ester derived, 9d)
Affinity DataIC50:  2.22E+3nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496890(indole chloropyridinyl-ester derived, 9f)
Affinity DataIC50:  4.43E+3nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627570(US11795159, Compound 7 | US11795159, Compound 8)
Affinity DataIC50:  5.50E+3nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496878(indole chloropyridinyl-ester derived, 7g)
Affinity DataIC50:  1.03E+4nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496889(indole chloropyridinyl-ester derived, 9e)
Affinity DataIC50:  1.53E+4nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627572(US11795159, Compound 10 | US11795159, Compound 9)
Affinity DataIC50:  5.50E+4nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627566(US11795159, Compound 3 | US11795159, Compound 6)
Affinity DataIC50:  5.50E+4nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627572(US11795159, Compound 10 | US11795159, Compound 9)
Affinity DataIC50:  5.50E+4nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627570(US11795159, Compound 7 | US11795159, Compound 8)
Affinity DataIC50:  5.50E+4nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496885(indole chloropyridinyl-ester derived, 9a)
Affinity DataIC50:  1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627576(US11795159, Compound 13 | US11795159, Compound 14)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627576(US11795159, Compound 13 | US11795159, Compound 14)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627564(US11795159, Compound 1 | US11795159, Compound 12)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627574(US11795159, Compound 11)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627568(US11795159, Compound 5)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627565(US11795159, Compound 2 | US11795159, Compound 4)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627566(US11795159, Compound 3 | US11795159, Compound 6)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627565(US11795159, Compound 2 | US11795159, Compound 4)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1a(2019-nCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM627564(US11795159, Compound 1 | US11795159, Compound 12)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using a recently described assay (Ghosh, A. K. et al. Bioorg. Med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(2019-nCoV)
Purdue University

LigandPNGBDBM496887(indole chloropyridinyl-ester derived, 9c)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 values were determined for compounds that covalently inhibit SARS-CoV-2 3CLpro using our recently described assay and data fitting methods that ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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