Affinity DataIC50: 0.220nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.320nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.760nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 8.20nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of MIP-1beta stimulated calcium transients in CCR5-expressing CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [125I]MIP-1alpha to human recombinant CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]-MIP-1 alpha from human C-C chemokine receptor type 5 expressed in CHO cellsMore data for this Ligand-Target Pair