Affinity DataKi: 0.580nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 0.950nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.29nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.31nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.81nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 2.81nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 3.85nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 4.03nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 4.68nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 4.85nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 5.02nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 9.24nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 13.4nMAssay Description:Inhibition of mouse ICEMore data for this Ligand-Target Pair
Affinity DataKi: 14.4nMAssay Description:Inhibition of mouse ICEMore data for this Ligand-Target Pair
Affinity DataKi: 16.7nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 16.9nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 17.9nMAssay Description:Displacement of [3H]AZD9272 from human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 18.7nMAssay Description:Inhibition of mouse ICEMore data for this Ligand-Target Pair
Affinity DataKi: 21.5nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]MPEP from human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 70.9nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 115nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 118nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataKi: 1.02E+3nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Negative allosteric modulation of rat recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracellu...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Negative allosteric modulation of rat recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracellu...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 4.77nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 8.5 T: 2°CAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 5.81nMAssay Description:Inhibition of human ICEMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair