Affinity DataIC50: 3.60nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of purified human Pank3 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of purified human Pank1beta using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetPantothenate kinase 2, mitochondrial(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of purified human Pank2 using d-[1-14C]pantothenate as substrate after 10 mins by radiochemical enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMT: 2°CAssay Description:Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...More data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMT: 2°CAssay Description:Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of recombinant human BRD2 bromodomain 2 (342 to 460 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by ...More data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of Pank3 (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
TargetPantothenate kinase 1(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of Pank1beta (unknown origin) by Kinase Glo HTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair