Compile Data Set for Download or QSAR
maximum 50k data
Found 306 with Last Name = 'sinha-roy' and Initial = 'r'
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50003020(MK-3102 | OMARIGLIPTIN | US10155775, Omarigliptin ...)
Affinity DataKi:  0.800nMAssay Description:Competitive reversible inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170939(CHEMBL3806052)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170919(CHEMBL3805966)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170922(CHEMBL3805629)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170923(CHEMBL3806041)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13528((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  0.290nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13527((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  0.490nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170929(CHEMBL3805751)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170953(CHEMBL3805154)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170921(CHEMBL3806023)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170957(CHEMBL3806157)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170952(CHEMBL3806310)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170934(CHEMBL3806021)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50212925((1S,2R,5S)-5-(5H-pyrrolo[3,4-d]pyrimidin-6(7H)-yl)...)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170920(CHEMBL3806029)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170956(CHEMBL3805294)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170927(CHEMBL3806216)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13526((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  0.910nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170936(CHEMBL3805179)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170959(CHEMBL3805226)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170931(CHEMBL3805871)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170955(CHEMBL3805937)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15553((3R,7R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50:  1.49nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170930(CHEMBL3805400)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170932(CHEMBL3805502)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50003020(MK-3102 | OMARIGLIPTIN | US10155775, Omarigliptin ...)
Affinity DataIC50:  1.60nMAssay Description:Competitive reversible inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170924(CHEMBL3805346)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170954(CHEMBL3804996)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13525((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15554((3R,7R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50:  2.77nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170935(CHEMBL3804950)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170940(CHEMBL3805353)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170926(CHEMBL3806003)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50212928((1S,2R,5S)-5-(2-cyclopropyl-5H-pyrrolo[3,4-d]pyrim...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15534((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  6.60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13519((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  6.60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13519((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  6.60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50212926((1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorop...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13515((3R)-3-amino-4-(2,5-difluorophenyl)-1-[(8R)-8-meth...)
Affinity DataIC50:  7.20nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170925(CHEMBL3806026)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210527((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydroimida...)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15538((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50170960(CHEMBL3804940)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15532((3R)-4-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoy...)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15539((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  9.60nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15543((3R,6S)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50:  9.70nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15536((3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)buta...)
Affinity DataIC50:  10.5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15555((3R,7R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50:  11nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM13518((3R)-4-[(3R)-3-amino-4-(2,5-difluorophenyl)butanoy...)
Affinity DataIC50:  11.5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM15530(1-substituted diazepanone 9b | methyl 2-[(3R)-4-[(...)
Affinity DataIC50:  11.6nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 306 total ) | Next | Last >>
Jump to: