Affinity DataKi: 0.0900nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
Affinity DataKi: 860nMAssay Description:Binding affinity towards trypsin was determinedMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Half-maximal inhibition of binding of [125I]CCK-8 to Cholecystokinin receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [125I]-CCK-8 binding to CCK receptors in rat pancreatic tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Half-maximal inhibition of binding of [125I]CCK-8 to Cholecystokinin receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assayMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]-CCK-8 binding to CCK receptors in rat pancreatic tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of [125I]-CCK-8 binding to CCK receptors in rat pancreatic tissueMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Half-maximal inhibition of binding of [125I]CCK-8 to Cholecystokinin receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of [125I]-CCK-8 binding to CCK receptors in rat pancreatic tissueMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of [125I]-CCK-8 binding to CCK receptors in rat pancreatic tissueMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of thrombin-catalyzed hydrolysis of a standard substrateMore data for this Ligand-Target Pair
TargetCytosolic phospholipase A2 beta(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assayMore data for this Ligand-Target Pair