TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Korea Research Institute Of Technology
Curated by ChEMBL
Korea Research Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PDE4DMore data for this Ligand-Target Pair