Compile Data Set for Download or QSAR
maximum 50k data
Found 1368 with Last Name = 'sotelo' and Initial = 'e'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50146585(CHEMBL3763396)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50443101(Cariprazine | RGH-188)
Affinity DataKi:  0.0850nMAssay Description:Partial agonist activity at human D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50161342(2-Amino-4-phenyl-indeno[1,2-d]pyrimidin-5-one | 2-...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]DPCPX from A1 adenosine receptor (unknown origin) expressed in CHO cell membrane incubated for 60 mins at room temperature by NXT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  0.340nMAssay Description:Partial agonist activity at human D2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))TBA
LigandPNGBDBM50613242(CHEMBL5271751)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in Wistar Han rat liver membrane assessed as inhibition constant incubated for 120 minsMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159502(CHEMBL3786849)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]OSIP339391 from human recombinant adenosine A2B receptor expressed in HEK293 cell membranes after 60 mins by liquid scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159502(CHEMBL3786849)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]OSIP339391 from human recombinant Adenosine A2B receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50268107(CHEMBL485862 | CHEMBL500634 | N-(2-(2-phenyl-6-(4-...)
Affinity DataKi:  0.5nMAssay Description:Antagonist activity at human A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50268107(CHEMBL485862 | CHEMBL500634 | N-(2-(2-phenyl-6-(4-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human recombinant A2B receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50268107(CHEMBL485862 | CHEMBL500634 | N-(2-(2-phenyl-6-(4-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to human recombinant A2B receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50613240(CHEMBL5278003)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to sigma 2 receptor in human MCF7 cells assessed as displacement of compound by measuring inhibition constant of DTG incubated for 1...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50048866(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Affinity DataKi:  0.680nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  0.800nMAssay Description:Partial agonist activity at human D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50584560(CHEMBL5077370)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50207816(CHEMBL273094 | N-(2-Amino-ethyl)-2-[4-(2,6-dioxo-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375415(CHEMBL259479)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375415(CHEMBL259479)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50542172(CHEMBL4632760)
Affinity DataKi:  1nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))TBA
LigandPNGBDBM50613231(CHEMBL5275443)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membranes assessed as inhibition constant by Wallac 1450 MicroBeta liqu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50161342(2-Amino-4-phenyl-indeno[1,2-d]pyrimidin-5-one | 2-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]SCH-58261 from A2A adenosine receptor (unknown origin) expressed in HEK cell membrane incubated for 60 mins at room temperature b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50375499(CHEMBL259319)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DPCPX from A1 adenosine receptor (unknown origin) expressed in CHO cell membrane incubated for 60 mins at room temperature by NXT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375414(CHEMBL260051)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375414(CHEMBL260051)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50584555(CHEMBL5084351)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cell membrane incubated for 60 mins by microbeta trilux scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50086168(2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...)
Affinity DataKi:  1.51nMAssay Description:Binding affinity to recombinant human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50410697(CHEMBL370588)
Affinity DataKi:  1.55nMAssay Description:Binding affinity to recombinant human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50584559(CHEMBL5088876)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50375500(CHEMBL259607)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cell membrane incubated for 60 mins by microbeta trilux scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]4-(2-[7-amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol from human adenosine A2A receptor expressed ...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]ZM2421385 from adenosine A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by scintillation counting meth...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]ZM241385 from human Adenosine A2A receptor expressed in HeLa cells after 30 minsMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]ZM241385/[125I]IABOPX from human recombinant adenosine A2B receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]ZM241385 from human recombinant A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by radioligand binding ...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM21190(4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-...)
Affinity DataKi:  1.90nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50021080(2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...)
Affinity DataKi:  1.91nMAssay Description:Binding affinity to recombinant human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50542171(CHEMBL4645754)
Affinity DataKi:  2nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375411(CHEMBL412112)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375413(CHEMBL260692)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375413(CHEMBL260692)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50375411(CHEMBL412112)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]IABOPX from human recombinant Adenosine A2B receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  2nMAssay Description:Binding affinity to recombinant human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159488(CHEMBL3787197)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]NECA from human A3 receptor expressed in human HeLa cell membranes incubated for 180 mins by radioligand binding competition assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50159488(CHEMBL3787197)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]NECA from human A3 receptor expressed in human HeLa cell membranes incubated for 180 mins by radioligand binding competition assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50086170((4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-di...)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universidade De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50584556(CHEMBL5086406)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]DPCPX from human A1AR expressed in CHO cell membrane incubated for 60 mins by microbeta trilux scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50086165(2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...)
Affinity DataKi:  2.14nMAssay Description:Binding affinity to recombinant human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1368 total ) | Next | Last >>
Jump to: