Compile Data Set for Download or QSAR
maximum 50k data
Found 6774 with Last Name = 'spencer' and Initial = 'j'
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103651(2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...)
Affinity DataKi:  0.0780nMAssay Description:Binding affinity for factor VIIa/TFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411339(CHEMBL227276)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50056102((R)-1-(1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-(pyridi...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411341(CHEMBL226583)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002875(CHEMBL388144)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411340(CHEMBL387948)
Affinity DataKi:  0.280nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50275119(1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411344(CHEMBL389711)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411342(CHEMBL227333)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411336(CHEMBL227330)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002880(CHEMBL437736)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161520(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103651(2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity of the compound towards urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103651(2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-b...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity of the compound towards Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161525(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350547(CHEMBL257307)
Affinity DataKi:  0.570nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411345(CHEMBL389639)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002878(CHEMBL227275)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350545(CHEMBL257305)
Affinity DataKi:  0.690nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002876(CHEMBL435143)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350546(CHEMBL1812708)
Affinity DataKi:  0.75nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002889(CHEMBL438843)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002902(CHEMBL226622)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002888(CHEMBL389713)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002872(CHEMBL437930)
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002926(CHEMBL244325)
Affinity DataKi:  0.910nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411348(CHEMBL226533)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411347(CHEMBL226620)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002895(CHEMBL226726)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002898(CHEMBL388068)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14338(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-nit...)
Affinity DataKi:  1.30nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002913(CHEMBL389783)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187167(CHEMBL211357 | N-[(S)-5-amino-1-(5-{4-[2-(3-chloro...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002877(CHEMBL388143)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187166(CHEMBL380293 | N-[(S)-5-amino-1-(5-{4-[2-(3-chloro...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187177(CHEMBL212774 | N-[(2S)-6-amino-1-{5-[(4-{[2-(3-chl...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187163((S)-benzyl 1-(5-(4-((3-chlorophenethyl)carbamoyl)b...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50002915(CHEMBL389787)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187160(CHEMBL213928 | N-[(2S)-6-amino-1-{5-[(4-{[2-(3-chl...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187168(CHEMBL377656 | N-[(2S)-6-amino-1-{5-[(4-{[2-(3-chl...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187176((S)-ethyl 1-(5-(4-((3-chlorophenethyl)carbamoyl)be...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411343(CHEMBL226675)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411338(CHEMBL227254)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187162((S)-N-(3-chlorophenethyl)-4-((3-(6-amino-2-pivalam...)
Affinity DataKi:  2nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50411346(CHEMBL226673)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Tryptase beta-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50187182((S)-N-(1-(5-(4-((3-chlorophenethyl)carbamoyl)benzy...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human beta tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14352(2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-indol-2-...)
Affinity DataKi:  2.20nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50100865((Z)-1-(oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-o...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 6774 total ) | Next | Last >>
Jump to: