Compile Data Set for Download or QSAR
maximum 50k data
Found 11 with Last Name = 'spilman' and Initial = 'ch'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataIC50:  300nMAssay Description:Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229236(CHEMBL46356)
Affinity DataIC50:  2.73E+3nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229241(CHEMBL295382)
Affinity DataIC50:  3.64E+3nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229233(CHEMBL299604)
Affinity DataIC50:  5.47E+3nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229237(CHEMBL47580)
Affinity DataIC50:  6.40E+3nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229239(CHEMBL297571)
Affinity DataIC50:  7.98E+3nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50039254(4-{(E)-2-[3-(5-Hydroxy-5-methyl-hexyl)-phenyl]-vin...)
Affinity DataIC50:  1.00E+4nMAssay Description:Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229235(CHEMBL46610)
Affinity DataIC50:  1.05E+4nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229234(CHEMBL416090)
Affinity DataIC50:  1.15E+4nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229238(CHEMBL297097)
Affinity DataIC50:  1.54E+4nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Upjohn

Curated by ChEMBL
LigandPNGBDBM50229240(CHEMBL417538)
Affinity DataIC50:  2.29E+4nMAssay Description:In vitro inhibition of Fu5AH acyl coenzyme A:cholesterol acyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed