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Found 648 with Last Name = 'stein' and Initial = 'hh'
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046798(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.240nMpH: 7.4Assay Description:In vitro inhibitory concentration against monkey plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022647(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.290nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022646(CHEMBL307917 | Morpholine-4-carboxylic acid {1-[1-...)
Affinity DataIC50:  0.300nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014049(CHEMBL287953 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.320nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022650(CHEMBL75117 | Morpholine-4-carboxylic acid {1-[1-(...)
Affinity DataIC50:  0.350nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006122(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.360nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280221((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.370nMpH: 6.0Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280229((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.380nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014052(CHEMBL445350 | {1-[1-(4-Azido-1-cyclohexylmethyl-2...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022643(4-Hydroxy-piperidine-1-carboxylic acid {1-[1-(1-cy...)
Affinity DataIC50:  0.420nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006125(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3-dihydroxy-5-...)
Affinity DataIC50:  0.470nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280237((1S,2R,3S)-2-(2-Methoxymethoxy-ethanesulfonyl)-3-p...)
Affinity DataIC50:  0.480nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022649(CHEMBL76458 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.5nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022645(CHEMBL75510 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.550nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022651(CHEMBL306274 | Morpholine-4-carboxylic acid {1-[1-...)
Affinity DataIC50:  0.580nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280235((1S,2S,3R)-2-Phenyl-3-(propane-2-sulfonyl)-cyclopr...)
Affinity DataIC50:  0.590nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011231(2-Benzyl-N-{1-[1-cyclohexylmethyl-2-(3-ethyl-2-oxo...)
Affinity DataIC50:  0.600nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280224((1S,2R,3S)-2-Methanesulfonyl-3-phenyl-cyclopropane...)
Affinity DataIC50:  0.630nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014059(CHEMBL38954 | {1-[1-[1-Cyclohexylmethyl-2-(3-ethyl...)
Affinity DataIC50:  0.630nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280222((1S,2R,3S)-2-Ethenesulfonyl-3-phenyl-cyclopropanec...)
Affinity DataIC50:  0.630nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022644(CHEMBL73712 | Piperazine-1-carboxylic acid {1-[1-(...)
Affinity DataIC50:  0.650nMpH: 6.0Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022643(4-Hydroxy-piperidine-1-carboxylic acid {1-[1-(1-cy...)
Affinity DataIC50:  0.680nMpH: 7.4Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280227((1S,2R,3S)-2-(2-Morpholin-4-yl-2-oxo-ethyl)-3-phen...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014060(CHEMBL288346 | {1-[1-{1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006138(2-(Morpholine-4-carbonyl)-3-phenyl-cyclopropanecar...)
Affinity DataIC50:  0.700nMpH: 6.0Assay Description:In vitro potency against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50405479(CHEMBL2028988)
Affinity DataIC50:  0.700nMAssay Description:Inhibition against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014048(CHEMBL41303 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  0.710nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046799(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.720nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046794(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.760nMpH: 7.4Assay Description:In vitro inhibitory concentration against monkey plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022653(CHEMBL309345 | Morpholine-4-carboxylic acid [1-[1-...)
Affinity DataIC50:  0.760nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280219(3-Benzenesulfonyl-2-benzyl-N-[(S)-1-((1S,2R,3S)-1-...)
Affinity DataIC50:  0.770nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50280231((1S,2R,3R)-2-Cyclohexyl-3-(propane-2-sulfonyl)-cyc...)
Affinity DataIC50:  0.790nMpH: 6.0Assay Description:In vitro inhibition of purified human renin at PH 6.0More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022641(2-Benzylidene-N-[1-(1-cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.790nMpH: 6.0Assay Description:Inhibition of purified human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046802(2-Benzyl-N*1*-[1-(1-cyclohexylmethyl-2,3-dihydroxy...)
Affinity DataIC50:  0.800nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50405497(CHEMBL2115482)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022654(CHEMBL265485 | Morpholine-4-carboxylic acid 1-[1-(...)
Affinity DataIC50:  0.820nMpH: 6.0Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014053(CHEMBL416429 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  0.840nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046796((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...)
Affinity DataIC50:  0.870nMpH: 7.4Assay Description:In vitro inhibition of human plasma renin at PH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50046796((S)-N-[(S)-1-((1S,2R,3S)-1-Cyclohexylmethyl-2,3-di...)
Affinity DataIC50:  0.870nMpH: 7.4Assay Description:Inhibitory concentration against human plasma renin at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022650(CHEMBL75117 | Morpholine-4-carboxylic acid {1-[1-(...)
Affinity DataIC50:  0.890nMpH: 7.4Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014063(CHEMBL290215 | {1-[1-[1-Cyclohexylmethyl-2-(4,4-di...)
Affinity DataIC50:  0.890nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006189((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  0.900nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006157(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  0.900nMpH: 6.0Assay Description:In vitro potency against plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014054((5R){1-[1-[1-Cyclohexylmethyl-2-hydroxy-2-(3-metho...)
Affinity DataIC50:  0.900nMAssay Description:In vitro inhibition of purified human renal renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006147(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  0.900nMpH: 7.4Assay Description:In vitro potency against purified renin at a pH of 6.0.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022642(CHEMBL74765 | Morpholine-4-carboxylic acid (1-{[1-...)
Affinity DataIC50:  0.940nMpH: 6.0Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50022645(CHEMBL75510 | N-[1-(1-Cyclohexylmethyl-2,3-dihydro...)
Affinity DataIC50:  0.980nMpH: 7.4Assay Description:Inhibition of human plasma renin (pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50011228((R)-2-Benzyl-N-[(S)-1-[(1S,2R)-1-cyclohexylmethyl-...)
Affinity DataIC50:  0.990nMpH: 6.5Assay Description:Compound was evaluated for the inhibitory concentration against purified human renal renin at pH 6.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006152(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014056(CHEMBL290605 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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