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Found 89 with Last Name = 'stephenson' and Initial = 'ra'
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054042((E)-6-(4-Hydroxy-7-methyl-3-oxo-6-vinyl-1,3-dihydr...)
Affinity DataIC50:  8.51nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)
Affinity DataIC50:  10nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054021((E)-6-(6-Ethyl-4-hydroxy-7-methyl-3-oxo-1,3-dihydr...)
Affinity DataIC50:  12.6nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054019((E)-6-(4-Hydroxy-6,7-dimethyl-3-oxo-1,3-dihydro-is...)
Affinity DataIC50:  18.6nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  24.8nMpH: 8.0Assay Description:Compound was tested for inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase at pH 8.0More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM19264((4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dih...)
Affinity DataIC50:  25nMpH: 8.0Assay Description:Compound was tested for inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase at pH 8.0More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053997((E)-6-(3-Chloro-2-hydroxy-6-methoxy-4,5-dimethyl-p...)
Affinity DataIC50:  33.5nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054004((E)-6-(3-Bromo-2-hydroxy-6-methoxy-4,5-dimethyl-ph...)
Affinity DataIC50:  36.7nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054002((E)-6-(6-Cyclopropyl-4-hydroxy-7-methyl-3-oxo-1,3-...)
Affinity DataIC50:  50.7nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054020((E)-6-(3-Chloro-2-hydroxy-4,5,6-trimethyl-phenyl)-...)
Affinity DataIC50:  69.3nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227206(CHEMBL66522)
Affinity DataIC50:  70nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000334(6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]quinazolin-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054017((E)-6-(4,6-Dihydroxy-7-methyl-3-oxo-1,3-dihydro-is...)
Affinity DataIC50:  87.7nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054034((E)-6-(6-Ethoxy-4-hydroxy-7-methyl-3-oxo-1,3-dihyd...)
Affinity DataIC50:  89.8nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054032((E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihy...)
Affinity DataIC50:  121nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054016((E)-6-(4-Hydroxy-6,7-dimethoxy-3-oxo-1,3-dihydro-i...)
Affinity DataIC50:  126nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053992((E)-6-(4-Hydroxy-7-methyl-3-oxo-6-phenyl-1,3-dihyd...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053989((E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-indan-5-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50225945(CI-930)
Affinity DataIC50:  150nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227195(CHEMBL31580)
Affinity DataIC50:  150nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054027((E)-6-(2-Hydroxy-6-methoxy-4,5-dimethyl-3-nitro-ph...)
Affinity DataIC50:  184nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054008((E)-6-(6-Carbamoyl-4-hydroxy-7-methyl-3-oxo-1,3-di...)
Affinity DataIC50:  231nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227207(Quazinone | Ro-136438 | Ro-136438006)
Affinity DataIC50:  240nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054015((E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-2,3-dihy...)
Affinity DataIC50:  244nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053993((E)-6-(2-Hydroxy-4,5,6-trimethyl-3-nitro-phenyl)-4...)
Affinity DataIC50:  289nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50226555(CHEMBL67513)
Affinity DataIC50:  290nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053994((E)-6-(7-Ethyl-4-hydroxy-6-methoxy-3-oxo-1,3-dihyd...)
Affinity DataIC50:  410nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054029((E)-6-(4-Hydroxy-6-methoxy-1,7-dimethyl-3-oxo-1,3-...)
Affinity DataIC50:  420nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054043((E)-6-(3-Chloro-2-fluoro-6-methoxy-4,5-dimethyl-ph...)
Affinity DataIC50:  437nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054003((E)-6-(2-Amino-3-bromo-6-methoxy-4,5-dimethyl-phen...)
Affinity DataIC50:  462nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054018((E)-6-(2-Amino-6-methoxy-4,5-dimethyl-3-nitro-phen...)
Affinity DataIC50:  465nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053998((E)-6-(2-Amino-3-chloro-6-methoxy-4,5-dimethyl-phe...)
Affinity DataIC50:  489nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054039((E)-6-(4-Hydroxy-6-methoxy-3-oxo-1,3-dihydro-isobe...)
Affinity DataIC50:  515nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227200(CHEMBL66978)
Affinity DataIC50:  520nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054040((E)-6-(3-Cyano-2-hydroxy-6-methoxy-4,5-dimethyl-ph...)
Affinity DataIC50:  534nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054013((E)-6-(5-Chloro-2-methoxy-3,4-dimethyl-phenyl)-4-m...)
Affinity DataIC50:  537nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054012((E)-6-(2,3-Dichloro-6-methoxy-4,5-dimethyl-phenyl)...)
Affinity DataIC50:  557nMAssay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase at 100 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227199(CHEMBL66447)
Affinity DataIC50:  560nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054025((E)-6-(2-Hydroxy-3-iodo-6-methoxy-4,5-dimethyl-phe...)
Affinity DataIC50:  592nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227194(CHEMBL66153)
Affinity DataIC50:  600nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054045((E)-6-(3-Bromo-2-hydroxy-4,5,6-trimethyl-phenyl)-4...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50053999((E)-6-(8-Hydroxy-6-methoxy-5-methyl-1-oxo-isochrom...)
Affinity DataIC50:  644nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054024((E)-6-(2-Chloro-3-cyano-6-methoxy-4,5-dimethyl-phe...)
Affinity DataIC50:  681nMAssay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase at 100 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50227196(CHEMBL66061)
Affinity DataIC50:  700nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054007((E)-6-(2-Amino-3-bromo-4,5,6-trimethyl-phenyl)-4-m...)
Affinity DataIC50:  763nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054033((E)-6-(5-Bromo-2-methoxy-3,4-dimethyl-phenyl)-4-me...)
Affinity DataIC50:  795nMAssay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase at 100 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM15296(6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin...)
Affinity DataIC50:  860nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054009((E)-6-(2-Hydroxy-6-methoxy-3,4,5-trimethyl-phenyl)...)
Affinity DataIC50:  959nMAssay Description:Inhibition of human recombinant inosine monophosphate dehydrogenase type II .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054041((E)-6-(7-Bromo-4-hydroxy-6-methoxy-3-oxo-1,3-dihyd...)
Affinity DataIC50:  975nMpH: 8.0Assay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase. at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50054047((E)-6-(3-Bromo-2-chloro-6-methoxy-4,5-dimethyl-phe...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human recombinant type II Inosine Monophosphate Dehydrogenase at 100 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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