TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.123nMAssay Description:Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pMMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pMMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Compound was tested in vitro for its ability to inhibit rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of solubilized partially purified rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair