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Found 62 with Last Name = 'strimpler' and Initial = 'am'
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041291(2-[(R)-3-(1,1-Dimethyl-2-phenyl-ethyl)-2,4,8-triox...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036058(CHEMBL354883 | benzyl (S)-1-((S)-2-(((S)-1,1,1-tri...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051162(CHEMBL13753 | {(R)-2,4,8-Trioxo-6-phenyl-7-[(3,3,3...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036127(CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036127(CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051160(2-[(R)-3-(4-Methoxy-benzyl)-2,4,8-trioxo-6-phenyl-...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051147(2-[(R)-3-(2-Ethoxy-ethyl)-2,4,8-trioxo-6-phenyl-2,...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037375(CHEMBL275043 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro...)
Affinity DataKi:  8nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051143(2-[(R)-3-(2-Morpholin-4-yl-ethyl)-2,4,8-trioxo-6-p...)
Affinity DataKi:  8.40nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051137(2-[(R)-3-(Benzylcarbamoyl-methyl)-2,4,8-trioxo-6-p...)
Affinity DataKi:  9.90nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051156(2-((R)-3-Methyl-2,4,8-trioxo-6-phenyl-2,3,4,8-tetr...)
Affinity DataKi:  10nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037100(2,2-Dimethyl-propionic acid 3-{5-benzyloxycarbonyl...)
Affinity DataKi:  12nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051158(2-[(R)-3-(2,2-Dimethoxy-ethyl)-2,4,8-trioxo-6-phen...)
Affinity DataKi:  12nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051150(2-{(R)-2,4,8-Trioxo-6-phenyl-7-[(3,3,3-trifluoro-1...)
Affinity DataKi:  15nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051139(CHEMBL13863 | N-(3,3,3-Trifluoro-1-isopropyl-2-oxo...)
Affinity DataKi:  15nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051155(2-[(R)-3-(1,1-Dimethyl-2-phenyl-ethyl)-2,4,8-triox...)
Affinity DataKi:  16nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037352(2-[2-Oxo-6-phenyl-3-((S)-3-pyridin-4-ylmethyl-urei...)
Affinity DataKi:  16nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051159(2-((R)-3-Dimethylamino-2,4,8-trioxo-6-phenyl-2,3,4...)
Affinity DataKi:  19nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051144(2-[(R)-3-(2-Naphthalen-1-yl-ethyl)-2,4,8-trioxo-2,...)
Affinity DataKi:  21nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051152(2-((R)-3-Methylcarbamoylmethyl-2,4,8-trioxo-6-phen...)
Affinity DataKi:  22nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051135(2-((R)-3-Naphthalen-1-ylmethyl-2,4,8-trioxo-2,3,4,...)
Affinity DataKi:  26nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037117(2,2-Dimethyl-propionic acid 4-{5-benzyloxycarbonyl...)
Affinity DataKi:  32nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037111(CHEMBL104303 | {5-(4-Hydroxy-benzyl)-2-oxo-1-[(3,3...)
Affinity DataKi:  34nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037102(CHEMBL75936 | {2-Oxo-5-[3-(2,2,2-trifluoro-acetyla...)
Affinity DataKi:  36nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037110(CHEMBL107291 | {5-Benzyl-2-oxo-1-[(3,3,3-trifluoro...)
Affinity DataKi:  40nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037105(Acetic acid 3-{5-benzyloxycarbonylamino-6-oxo-1-[(...)
Affinity DataKi:  42nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051141(CHEMBL14064 | N-(3,3,3-Trifluoro-1-isopropyl-2-oxo...)
Affinity DataKi:  42nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051136(CHEMBL13740 | {(R)-2,4,8-Trioxo-7-[(3,3,3-trifluor...)
Affinity DataKi:  44nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037113(CHEMBL104289 | [2-Oxo-1-[(3,3,3-trifluoro-1-isopro...)
Affinity DataKi:  47nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037116(CHEMBL107966 | N-{5-Benzyl-2-oxo-1-[(3,3,3-trifluo...)
Affinity DataKi:  48nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037098(CHEMBL104032 | N-{5-Benzyl-2-oxo-1-[(3,3,3-trifluo...)
Affinity DataKi:  51nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037346(2-(3-Amino-2-oxo-6-phenyl-2H-pyridin-1-yl)-N-(3,3,...)
Affinity DataKi:  62nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037118(CHEMBL106793 | N-{5-Benzyl-2-oxo-1-[(3,3,3-trifluo...)
Affinity DataKi:  70nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037099(CHEMBL104557 | {5-(4-Fluoro-benzyl)-2-oxo-1-[(3,3,...)
Affinity DataKi:  71nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051148(CHEMBL14222 | N-(3,3,3-Trifluoro-1-isopropyl-2-oxo...)
Affinity DataKi:  74nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037106(CHEMBL106066 | {5-(3-Fluoro-benzyl)-2-oxo-1-[(3,3,...)
Affinity DataKi:  87nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037107(4-{5-Benzyloxycarbonylamino-6-oxo-1-[(3,3,3-triflu...)
Affinity DataKi:  88nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037103(CHEMBL106888 | {5-(3-Hydroxy-benzyl)-2-oxo-1-[(3,3...)
Affinity DataKi:  89nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051138(2-[(R)-3-(4-Methoxy-benzyl)-2,4,8-trioxo-2,3,4,8-t...)
Affinity DataKi:  100nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051149(2-((R)-3-Benzyl-2,4,8-trioxo-2,3,4,8-tetrahydro-1H...)
Affinity DataKi:  160nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051161(CHEMBL276181 | N-(3,3,3-Trifluoro-1-isopropyl-2-ox...)
Affinity DataKi:  230nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037109(CHEMBL13684 | {2-Oxo-1-[(3,3,3-trifluoro-1-isoprop...)
Affinity DataKi:  280nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037109(CHEMBL13684 | {2-Oxo-1-[(3,3,3-trifluoro-1-isoprop...)
Affinity DataKi:  280nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037109(CHEMBL13684 | {2-Oxo-1-[(3,3,3-trifluoro-1-isoprop...)
Affinity DataKi:  280nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051154(CHEMBL14176 | {(R)-2,4,8-Trioxo-7-[(3,3,3-trifluor...)
Affinity DataKi:  290nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051142(CHEMBL13804 | N-(3,3,3-Trifluoro-1-isopropyl-2-oxo...)
Affinity DataKi:  310nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037097(CHEMBL105124 | N-{2-Oxo-1-[(3,3,3-trifluoro-1-isop...)
Affinity DataKi:  320nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051140(2-[(R)-3-(2-Morpholin-4-yl-ethyl)-2,4,8-trioxo-2,3...)
Affinity DataKi:  330nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037108(CHEMBL104050 | N-{2-Oxo-1-[(3,3,3-trifluoro-1-isop...)
Affinity DataKi:  350nMAssay Description:The compound was tested in vitro for ability to inhibit human leukocyte elastase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037357(2-[3-((S)-2-Morpholin-4-yl-acetylamino)-2-oxo-6-ph...)
Affinity DataKi:  469nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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