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Found 46 with Last Name = 'su' and Initial = 'cr'
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544153(CHEMBL4088476)
Affinity DataKi:  5.45E+3nMAssay Description:Binding affinity to recombinant human cathepsin KMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544158(CHEMBL4646253)
Affinity DataKi:  9.57E+3nMAssay Description:Binding affinity to recombinant human cathepsin KMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50292332(2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]i...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226670(CHEMBL251055 | jatrorrhizine)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544154(CHEMBL4069931)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226662(CHEMBL251229 | stepharanine)
Affinity DataIC50: >2.50E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544153(CHEMBL4088476)
Affinity DataIC50:  3.35E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544155(CHEMBL4080607)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50260364(CHEMBL4065603)
Affinity DataIC50:  5.36E+3nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorogenic Z-FR-MCA as substrate preincubated for 5 mins followed by substrate addition by spectrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50260364(CHEMBL4065603)
Affinity DataIC50:  5.72E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544158(CHEMBL4646253)
Affinity DataIC50:  6.44E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544156(CHEMBL4072655)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50260365(CHEMBL4096825)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544157(CHEMBL4645935)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Phe-Arg-MCA as fluorogenic substrate preincubated for 5 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50242128(CHEMBL511822 | Taraxerol, 8 | taraxerol)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50098937((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226664(2-hydroxy-3,9,10-trimethoxy-5,6-dihydroisoquino[3,...)
Affinity DataIC50:  3.06E+4nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50275506(CHEMBL519077 | taraxerone)
Affinity DataIC50:  4.65E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50275563((+)-pinitol | (1R,2S,3R,4S,5S,6S)-6-methoxycyclohe...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50275562((3S,5R,6R,7E,9R)-megastigman-7-ene-3,5,6,9-tetraol...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50223401(CHEMBL251450 | echinulin)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50276058(CHEMBL469505 | Norerythrofordin A)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50242248(CHEMBL461060 | beta-amyrenone | beta-amyrinone | o...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50260203(CHEMBL489760 | Germanicol 3-acetate | beta-amyrin ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50241943(CHEMBL485998 | Friedeline | friedelin)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50275350(CHEMBL487567 | Glutinol acetate | glutin-5-en-3-be...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50269628(CHEMBL517609 | glutinone)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50242187(5-stigmasten-3beta,7beta-diol | 7beta-hydroxysitos...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50275507(5-alpha-stigmasta-7,22-diene-3beta-ol | CHEMBL4877...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50275561(CHEMBL487767 | stigmast-4-ene-3beta,6beta-diol)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50213414(CHEMBL240528 | afzelin | kaempferol 3-O-alpha-L-rh...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50242217(CHEMBL452242 | Glutinol | glut-5-en-3-ol)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544160(CHEMBL4647489)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorogenic Z-FR-MCA as substrate preincubated for 5 mins followed by substrate addition by spectrof...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Federal University Of S£O Carlos

Curated by ChEMBL
LigandPNGBDBM50544159(CHEMBL4638651)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of cathepsin L (unknown origin) using fluorogenic Z-FR-MCA as substrate preincubated for 5 mins followed by substrate addition by spectrof...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226672(CHEMBL255034 | makisterone A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226667(CHEMBL399731 | fibraurinoside)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226665(CHEMBL398472 | fibrauretin A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226663(CHEMBL251672 | epi-12-palmatoside G)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226661(CHEMBL254592 | fibraurecdyside A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226673(CHEMBL399973 | fibleucinoside)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226668(CHEMBL249243 | epi-fibrauretinoside A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50226671(CHEMBL400494 | fibrauretinoside A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli assessed as inhibition of nifedipine oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50242238(ACROVESTONE | CHEMBL513957)
Affinity DataIC50:  3.33E+5nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed