Affinity DataKi: 0.574nMAssay Description:Displacement of [33P]-S1P from human S1P5 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.626nMAssay Description:Agonist activity at human S1P5 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by E...More data for this Ligand-Target Pair
Affinity DataKi: 0.772nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [33P]-S1P from human S1P4 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >5.45E+3nMAssay Description:Displacement of [33P]-S1P from rat S1P1 receptor after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: >5.63E+3nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.784nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at human recombinant OX1R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist activity at human recombinant OX2R expressed in CHOK1 cells assessed as inhibition of orexin A-induced intracellular Ca2+ release preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells.More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Human Factor XIa activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6000, 50 mM HEPES-NaOH (pH7.4) wit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMpH: 7.4 T: 2°CAssay Description:The antagonistic activities of the test compounds on human orexin-1 receptor (hOX1R) and orexin-2 receptor (hOX2R) were measured by modifying from th...More data for this Ligand-Target Pair