Compile Data Set for Download or QSAR
maximum 50k data
Found 16 with Last Name = 'taishi' and Initial = 't'
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50062551(CHEBI:76010 | Dolutegravir | GSK1349572 | S-349572)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50483553(CHEBI:76007 | Dolutegravir Sodium | GSK1349572 | G...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of strand transfer activity of Human immunodeficiency virus 1 Integrase using [3H]labeled target DNA as substrate after 45 mins by scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50492496(Cabotegravir | GSK-1265744A | GSK1265744 | GSK1265...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50480673(Isentress | Isentress hd | MK-0518 | MK-0518 POTAS...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of strand transfer activity of Human immunodeficiency virus 1 Integrase using [3H]labeled target DNA as substrate after 45 mins by scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50492497(CHEMBL2403118)
Affinity DataIC50:  5nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity using [3H]-DNA as substrate preincubated for 60 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)
Affinity DataIC50:  6nMAssay Description:Inhibition of strand transfer activity of Human immunodeficiency virus 1 Integrase using [3H]labeled target DNA as substrate after 45 mins by scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Shionogi

US Patent
LigandPNGBDBM541768(5-Hydroxy-1-isobutyl-6,10-dioxo-1,2,3,4,6,9,9a,10-...)
Affinity DataIC50:  8.30nMAssay Description:Streptavidin (manufactured by Vector Laboratories) was dissolved in a 0.1M carbonate buffer solution (composition: 90 nM Na2CO3, 10 mM NaHCO3) to a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Shionogi

US Patent
LigandPNGBDBM541769(5-Hydroxy-6,10-dioxo-3,4,6,9,9a,10-hexahydro-2H-1-...)
Affinity DataIC50:  8.30nMAssay Description:Streptavidin (manufactured by Vector Laboratories) was dissolved in a 0.1M carbonate buffer solution (composition: 90 nM Na2CO3, 10 mM NaHCO3) to a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Shionogi

US Patent
LigandPNGBDBM541767(5-Hydroxy-4,6-dioxo-2,3,4,6,9,9a-hexahydro-1-oxa-3...)
Affinity DataIC50:  9nMAssay Description:Streptavidin (manufactured by Vector Laboratories) was dissolved in a 0.1M carbonate buffer solution (composition: 90 nM Na2CO3, 10 mM NaHCO3) to a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485874(CHEMBL2171671)
Affinity DataIC50:  10nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485875(CHEMBL2171670)
Affinity DataIC50:  18nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485873(CHEMBL2171665)
Affinity DataIC50:  130nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485877(CHEMBL2171666)
Affinity DataIC50:  300nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485876(CHEMBL2171667)
Affinity DataIC50:  380nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485871(CHEMBL2171669)
Affinity DataIC50:  540nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50485872(CHEMBL2171668)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activity using pre-incubation and wash with Mg2+ cofactor by ELISA based microtiter plate integration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed