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Found 72 with Last Name = 'takebe' and Initial = 't'
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM18012(trans,trans-4-arylpiperidine-based compound, 1)
Affinity DataIC50:  0.0670nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of renin activity in human plasmaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598954(CHEMBL5187830)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601200(CHEMBL5203297)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50598954(CHEMBL5187830)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM17950((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601198(CHEMBL5186584)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601192(CHEMBL5176733)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM18012(trans,trans-4-arylpiperidine-based compound, 1)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of renin activity in human plasmaMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601195(CHEMBL5174842)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601199(CHEMBL5170164)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM149462(US8975252, 39)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601194(CHEMBL5197721)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601196(CHEMBL5203591)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM149461(US8975252, 4)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601192(CHEMBL5176733)
Affinity DataIC50:  54nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601194(CHEMBL5197721)
Affinity DataIC50:  74nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM149462(US8975252, 39)
Affinity DataIC50:  84nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601195(CHEMBL5174842)
Affinity DataIC50:  103nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601197(CHEMBL5188797)
Affinity DataIC50:  103nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601190(CHEMBL5183309)
Affinity DataIC50:  118nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601189(CHEMBL5206846)
Affinity DataIC50:  158nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601193(CHEMBL5185167)
Affinity DataIC50:  274nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM149461(US8975252, 4)
Affinity DataIC50:  290nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50186512(CHEMBL377810 | benzyl 6-benzyl-2-hydroxy-5-oxo-5,6...)
Affinity DataIC50:  500nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601186(CHEMBL5181888)
Affinity DataIC50:  583nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50186512(CHEMBL377810 | benzyl 6-benzyl-2-hydroxy-5-oxo-5,6...)
Affinity DataIC50:  700nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601186(CHEMBL5181888)
Affinity DataIC50:  770nMAssay Description:Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50186500(1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one | ...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186507((5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone | CHEMB...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186507((5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone | CHEMB...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186500(1-benzoyl-2-benzyl-1,2-dihydropyridin-3(6H)-one | ...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186513(CHEMBL212569 | benzyl 6-benzyl-5-oxo-5,6-dihydropy...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186510((2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone | CHE...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186504(2-benzyl-1-(phenylsulfonyl)-1,2-dihydropyridin-3(6...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186506((5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone | ...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186502(CHEMBL210178 | methyl 6-benzyl-5-oxo-5,6-dihydropy...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186513(CHEMBL212569 | benzyl 6-benzyl-5-oxo-5,6-dihydropy...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186502(CHEMBL210178 | methyl 6-benzyl-5-oxo-5,6-dihydropy...)
Affinity DataIC50:  9.80E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601187(CHEMBL5177567)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601188(CHEMBL5187637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601191(CHEMBL5176378)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50186506((5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone | ...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601184(CHEMBL5199179)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50186504(2-benzyl-1-(phenylsulfonyl)-1,2-dihydropyridin-3(6...)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50186510((2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone | CHE...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50601182(CHEMBL5205574)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50186508((5R,6S)-5-(benzyloxy)-6-methoxycyclohex-2-enone | ...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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