Affinity DataIC50: 0.0670nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of renin activity in human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of renin activity in human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 274nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of renin activity in human plasma by competitive radio immunoassayMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
Affinity DataIC50: 583nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIAMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of beta amyloid protein 40More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant renin using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp substrate incubated for 1 hr by FRETMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIAMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant renin using sheep recombinant angiotensinogen substrate incubated for 1 hr by EIAMore data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
University Of Tokyo
Curated by ChEMBL
University Of Tokyo
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of beta amyloid protein 42More data for this Ligand-Target Pair