TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine
Curated by ChEMBL
Institute For Theoretical Medicine
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine
Curated by ChEMBL
Institute For Theoretical Medicine
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine
Curated by ChEMBL
Institute For Theoretical Medicine
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase after 15 mins by Lineweaver-Bulk plot analysisMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine
Curated by ChEMBL
Institute For Theoretical Medicine
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of mushroom tyrosinase after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Institute For Theoretical Medicine
Curated by ChEMBL
Institute For Theoretical Medicine
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of mushroom tyrosinase after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 238nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 259nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 328nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT1 phosphorylationMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 375nMAssay Description:Inhibition of IKKbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 386nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT1 phosphorylationMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis
Curated by ChEMBL
Exelixis
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 447nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT3 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 452nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT3 phosphorylationMore data for this Ligand-Target Pair