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Found 1770 with Last Name = 'teng' and Initial = 'm'
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286349(US11220518, Ex. No. K7 | US11780853, Example K7 | ...)
Affinity DataKi:  0.165nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286349(US11220518, Ex. No. K7 | US11780853, Example K7 | ...)
Affinity DataKi:  0.165nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286349(US11220518, Ex. No. K7 | US11780853, Example K7 | ...)
Affinity DataKi:  0.165nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222915(4'-[5-(4-pyrrolidin-1-ylmethyl-phenylamino)-1H-pyr...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286350(US11220518, Ex. No. K8 | US11780853, Example K8 | ...)
Affinity DataKi:  0.181nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286350(US11220518, Ex. No. K8 | US11780853, Example K8 | ...)
Affinity DataKi:  0.181nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286350(US11220518, Ex. No. K8 | US11780853, Example K8 | ...)
Affinity DataKi:  0.181nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222916(4'-{5-[4-(dimethylamino-methyl)-phenylamino]-2H-py...)
Affinity DataKi:  0.190nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222920(4'-{5-[6-(sec-butylamino-methyl)-pyridin-3-ylamino...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222917(4'-[5-(6-piperidin-1-ylmethyl-pyridin-3-ylamino)-1...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222913(4'-{5-[4-(isopropylamino-methyl)-phenylamino]-2H-p...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286348(US11220518, Ex. No. K6 | US11780853, Example K6 | ...)
Affinity DataKi:  0.376nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286348(US11220518, Ex. No. K6 | US11780853, Example K6 | ...)
Affinity DataKi:  0.376nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286348(US11220518, Ex. No. K6 | US11780853, Example K6 | ...)
Affinity DataKi:  0.376nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222914(4'-[5-(4-cyclopropylaminomethyl-phenylamino)-2H-py...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222921(3-(1H-benzo[d]imidazol-2-yl)-N-(2,4-dihydroxypheny...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286347(US11220518, Ex. No. K5 | US11780853, Example K5 | ...)
Affinity DataKi:  0.683nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286347(US11220518, Ex. No. K5 | US11780853, Example K5 | ...)
Affinity DataKi:  0.683nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286347(US11220518, Ex. No. K5 | US11780853, Example K5 | ...)
Affinity DataKi:  0.683nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426188(CHEMBL2311920)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222919(4'-(5-{6-[(cyclopropylmethyl-amino)-methyl]-pyridi...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286345(US11220518, Ex. No. K3 | US11780853, Example K3 | ...)
Affinity DataKi:  0.912nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286345(US11220518, Ex. No. K3 | US11780853, Example K3 | ...)
Affinity DataKi:  0.912nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286345(US11220518, Ex. No. K3 | US11780853, Example K3 | ...)
Affinity DataKi:  0.912nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286246(5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...)
Affinity DataKi:  1.01nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286246(5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...)
Affinity DataKi:  1.01nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286246(5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...)
Affinity DataKi:  1.01nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM533472(US11220518, Ex. No. K1 | US11780853, Example K1)
Affinity DataKi:  1.12nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286343(N-(2-ethoxy-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5...)
Affinity DataKi:  1.12nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM533472(US11220518, Ex. No. K1 | US11780853, Example K1)
Affinity DataKi:  1.12nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286320(US9518060, Example J6)
Affinity DataKi:  1.17nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM533459(US11220518, Ex. No. J6 | US11780853, Example J6)
Affinity DataKi:  1.17nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM533459(US11220518, Ex. No. J6 | US11780853, Example J6)
Affinity DataKi:  1.17nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426188(CHEMBL2311920)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50222918(4'-(5-phenylamino-2H-pyrazol-3-yl)-biphenyl-2,4-di...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human CHK1 expressed in baculovirus/insect cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286270(US11220518, Ex. No. E2 | US11780853, Example E2 | ...)
Affinity DataKi:  1.64nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286270(US11220518, Ex. No. E2 | US11780853, Example E2 | ...)
Affinity DataKi:  1.64nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286270(US11220518, Ex. No. E2 | US11780853, Example E2 | ...)
Affinity DataKi:  1.64nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM153901(US8999981, A146)
Affinity DataKi:  1.70nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286377(US11220518, Ex. No. L4 | US11780853, Example L4 | ...)
Affinity DataKi:  1.71nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286377(US11220518, Ex. No. L4 | US11780853, Example L4 | ...)
Affinity DataKi:  1.71nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286377(US11220518, Ex. No. L4 | US11780853, Example L4 | ...)
Affinity DataKi:  1.71nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM286310(N-(5-fluoro-2-propylpyrimidin-4-yl)-6,6-dimethyl-5...)
Affinity DataKi:  1.73nMpH: 7.4Assay Description:Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM533452(US11220518, Ex. No. I1 | US11780853, Example I1)
Affinity DataKi:  1.73nMAssay Description:A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30° C. in 0.1 mL of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein kinase C beta type Isoform 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM533452(US11220518, Ex. No. I1 | US11780853, Example I1)
Affinity DataKi:  1.73nMAssay Description:Protein Kinase C beta 2 (PKCpII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate peptide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426183(CHEMBL2311925)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426182(CHEMBL2311926)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThreonine--tRNA ligase 1, cytoplasmic(Homo sapiens (Human))
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426182(CHEMBL2311926)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM153898(US8999981, A143)
Affinity DataKi:  1.90nM ΔG°:  -50.6kJ/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThreonine--tRNA ligase(Yersinia pestis)
Trius Therapeutics

Curated by ChEMBL
LigandPNGBDBM50426184(CHEMBL2311924)
Affinity DataKi:  2nMAssay Description:Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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