Affinity DataKi: 0.440nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:In vitro reversal of vecuronium-induced neuromuscular block in guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of recombinant human CA7 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nM ΔG°: -49.5kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -49.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human CA7 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of recombinant human CA7 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Inhibition of recombinant human CA12 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Inhibition of [125I]RTI-55 binding to Serotonin transporter of rat caudate membranesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 6.70nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Shri G.S. Institute Of Technology And Science
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Inhibition of recombinant human CA2 pre-incubated for 15 mins measured by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair