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Found 248 with Last Name = 'torino' and Initial = 'd'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295263((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295264((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295262((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320022((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  9.56nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  10.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295261(CHEMBL549770 | N-((S)-1-((S)-1-amino-1-oxo-3-pheny...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295265(CHEMBL540482 | N-((S)-1-((S)-1-amino-1-oxo-3-pheny...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295265(CHEMBL540482 | N-((S)-1-((S)-1-amino-1-oxo-3-pheny...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]DPDE from delta opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320023((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320024((S)-N-(3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylami...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295260(CHEMBL564939 | N-((S)-1-((S)-1-amino-1-oxo-3-pheny...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295261(CHEMBL549770 | N-((S)-1-((S)-1-amino-1-oxo-3-pheny...)
Affinity DataKi:  710nMAssay Description:Displacement of [3H]DPDE from delta opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295263((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [3H]DPDE from delta opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295264((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [3H]DPDE from delta opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50295260(CHEMBL564939 | N-((S)-1-((S)-1-amino-1-oxo-3-pheny...)
Affinity DataKi:  6.90E+3nMAssay Description:Displacement of [3H]DPDE from delta opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320023((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320022((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649268(2-Chloro-N-(2-{4-[(6-chloropyridin-2-yl)oxy]piperi...)
Affinity DataIC50:  11.1nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649300(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  11.3nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649255(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  11.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649217(2-Chloro-N-(2-{4-[(4-chloro-1,3-thiazol-2-yl)oxy]p...)
Affinity DataIC50:  11.8nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649264(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  11.9nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649223(N-{2-[4-(1,3-Benzoxazol-2-yloxy)piperidin-1-yl]-2-...)
Affinity DataIC50:  12.3nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649274(2-Chloro-N-[2-(4-{[(4-chloro-1,3-thiazol-2-yl)oxy]...)
Affinity DataIC50:  13nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649293(2-Chloro-N-[2-(4-{[(3-cyanopyridin-2-yl)oxy]methyl...)
Affinity DataIC50:  13.2nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649268(2-Chloro-N-(2-{4-[(6-chloropyridin-2-yl)oxy]piperi...)
Affinity DataIC50:  13.4nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649283(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  13.8nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649222(N-{2-[4-(1,3-Benzothiazol-2-yl oxy)piperidin-1-yl]...)
Affinity DataIC50:  14nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetMu-type opioid receptor(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataIC50:  15nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649284(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  15.2nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649273(2-chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  15.2nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649306(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  16.1nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649296(2-Chloro-N-[2-(4-{[(4-cyanopyridin-3-yl)oxy]methyl...)
Affinity DataIC50:  16.1nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649303(2-Chloro-N-[2-(4-{[(3-chloropyridin-2-yl)oxy]methy...)
Affinity DataIC50:  16.4nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649261(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  16.6nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649229(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  17.3nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649222(N-{2-[4-(1,3-Benzothiazol-2-yl oxy)piperidin-1-yl]...)
Affinity DataIC50:  17.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649297(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  17.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649305(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  18.1nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649305(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  18.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649218(2-Chloro-N-(2-{4-[(3-cyclopropyl-1,2,4-thiadiazol-...)
Affinity DataIC50:  19.2nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649294(2-Chloro-N-[2-(4-{[(6-cyanopyridin-2-yl)oxy]methyl...)
Affinity DataIC50:  19.2nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649247(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  19.4nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Mus musculus)
Breye Therapeutics

US Patent
LigandPNGBDBM649247(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  19.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649279(2-Chloro-N-[2-(4-{[(2-cyanopyridin-3-yl)oxy]methyl...)
Affinity DataIC50:  20nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649272(2-chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  20.1nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649271(2-Chloro-N-{2-[4-(difluoromethyl)-1,3-thiazol-5-yl...)
Affinity DataIC50:  20.3nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Breye Therapeutics

US Patent
LigandPNGBDBM649223(N-{2-[4-(1,3-Benzoxazol-2-yloxy)piperidin-1-yl]-2-...)
Affinity DataIC50:  20.5nMAssay Description:Extracellular binding of Bz-ATP to P2X7 receptor opens the channel and allows Ca2+ influx into the cells. This Ca2+ entry was measured in HEK-293 cel...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
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