Affinity DataKi: 6nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Binding affinity against Muscarinic acetylcholine receptor was determined in homogenized rat cortex tissue using [3H]N-methylscopolamine as radioliga...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Binding affinity towards muscarinic receptor of gastric fundus containing Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Binding affinity towards muscarinic receptor of cerebral cortex containing Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Binding affinity towards muscarinic receptor of cerebral cortex containing Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Binding affinity towards muscarinic receptor of cerebral cortex containing Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Binding affinity towards muscarinic receptor of gastric fundus containing Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Binding affinity for glandular muscarinic acetylcholine receptor M3 in rat assayed using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 productionMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity towards muscarinic receptor of gastric fundus containing Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity towards muscarinic receptor of cerebral cortex containing Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity towards muscarinic receptor of cerebral cortex containing Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity towards muscarinic receptor of gastric fundus containing Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Binding affinity towards muscarinic receptor of gastric fundus containing Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Binding affinity to the rat cardiac muscarinic acetylcholine receptor M2 using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Binding affinity towards Muscarinic acetylcholine receptor M1 of cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Binding affinity for glandular muscarinic acetylcholine receptor M3 in rat assayed using 0.3 nM [3H]-N-methylscopolamine as radioligandMore data for this Ligand-Target Pair