Compile Data Set for Download or QSAR
maximum 50k data
Found 36 with Last Name = 'umehara' and Initial = 'k'
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.820nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  4.90nMAssay Description:Binding affinity to human ERRgammaMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  62nMAssay Description:Binding affinity to human ERRgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  80nMAssay Description:Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261553(CHEMBL4087989)
Affinity DataIC50:  154nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261553(CHEMBL4087989)
Affinity DataIC50:  169nMAssay Description:Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  226nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261555(CHEMBL4088694)
Affinity DataIC50:  294nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261555(CHEMBL4088694)
Affinity DataIC50:  306nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  341nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261551(CHEMBL4094003)
Affinity DataIC50:  915nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261554(CHEMBL4092300)
Affinity DataIC50:  939nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261554(CHEMBL4092300)
Affinity DataIC50:  1.08E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  1.53E+3nMAssay Description:Antagonist activity at full length ERbeta (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261556(CHEMBL4105062)
Affinity DataIC50:  1.65E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261557(CHEMBL4071813)
Affinity DataIC50:  1.68E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261551(CHEMBL4094003)
Affinity DataIC50:  1.69E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261556(CHEMBL4105062)
Affinity DataIC50:  1.98E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261557(CHEMBL4071813)
Affinity DataIC50:  2.53E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERbeta-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261558(CHEMBL4071506)
Affinity DataIC50:  2.65E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310832(CHEMBL1080779 | Clinopodic acid C)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261552(CHEMBL4066690)
Affinity DataIC50:  3.51E+3nMAssay Description:Displacement of [3H]spiperone from human D2SR expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261552(CHEMBL4066690)
Affinity DataIC50:  5.34E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261551(CHEMBL4094003)
Affinity DataIC50:  9.39E+3nMAssay Description:Antagonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50250808(CHEMBL518243 | lithospermic acid)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50133496((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310829(CHEMBL1081512 | clinopodic acid E)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310827(CHEMBL1079357 | clinopodic acid H)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310828(CHEMBL1079356 | clinopodic acid F)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310831(CHEMBL1079231 | Clinopodic acid A)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50310830(CHEMBL1080778 | Clinopodic acid B)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Rattus norvegicus (Rat))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210054((R,E)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropa...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of gelatinolytic activity of MMP2 in rat lung homogenate after 40 mins by SDS-PAGE preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261554(CHEMBL4092300)
Affinity DataEC50:  1.33E+3nMAssay Description:Displacement of [3H]E2 from GST-fused ERalpha-LBD (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261553(CHEMBL4087989)
Affinity DataEC50:  1.44E+3nMAssay Description:Agonist activity at full length ERalpha (unknown origin) expressed in human HeLa cells incubated for 24 hrs by ERE-driven luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50261555(CHEMBL4088694)
Affinity DataEC50:  7.40E+3nMAssay Description:Displacement of [3H]spiperone from human D2SR expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed