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Found 877 with Last Name = 'uno' and Initial = 'y'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202150(US9233983, I-20)
Affinity DataIC50:  0.550nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50237672(CHEMBL4089159)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant human Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus expression syst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202149(US9233983, I-19)
Affinity DataIC50:  0.650nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202226(US9233983, R-5)
Affinity DataIC50:  0.75nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM364370(4-[3-(2,6-dichlorobenzoyl)-7-fluoro-1H-indol-1-yl]...)
Affinity DataIC50:  1nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202200(US9233983, P-15)
Affinity DataIC50:  1nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202199(US9233983, P-14)
Affinity DataIC50:  1nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202198(US9233983, P-13)
Affinity DataIC50:  1nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202131(US9233983, I-2)
Affinity DataIC50:  1nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202215(US9233983, P-30)
Affinity DataIC50:  1nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512498(CHEMBL4570491)
Affinity DataIC50:  1.10nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202220(US9233983, Q-3)
Affinity DataIC50:  1.15nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202212(US9233983, P-27)
Affinity DataIC50:  1.20nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202207(US9233983, P-22)
Affinity DataIC50:  1.20nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202214(US9233983, P-29)
Affinity DataIC50:  1.30nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202147(US9233983, I-17)
Affinity DataIC50:  1.30nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174187(US9102637, 222)
Affinity DataIC50:  1.30nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202201(US9233983, P-16)
Affinity DataIC50:  1.30nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202208(US9233983, P-23)
Affinity DataIC50:  1.40nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202144(US9233983, I-15)
Affinity DataIC50:  1.5nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202223(US9233983, R-2)
Affinity DataIC50:  1.5nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512490(CHEMBL4454027)
Affinity DataIC50:  1.60nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202225(US9233983, R-4)
Affinity DataIC50:  1.60nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202145(US9233983, I-16)
Affinity DataIC50:  1.60nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174104(US9102637, 139)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202122(US9233983, D-14)
Affinity DataIC50:  1.70nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202203(US9233983, P-18)
Affinity DataIC50:  1.70nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202143(US9233983, I-14)
Affinity DataIC50:  1.70nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202148(US9233983, I-18)
Affinity DataIC50:  1.90nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50203542(CHEMBL3218921)
Affinity DataIC50:  2nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Advinus Therapeutics

Curated by ChEMBL
LigandPNGBDBM50512497(CHEMBL4567440)
Affinity DataIC50:  2nMAssay Description:Inverse agonist activity at GST-tagged RORgammat LBD (unknown origin) using fluorescein-D22 co-activator peptide as substrate incubated for 1 hr by T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202117(US9233983, D-9)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202091(US9233983, B-10)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202189(US9233983, P-5)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202174(US9233983, K-22)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202142(US9233983, I-13)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202141(US9233983, I-12)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202136(US9233983, I-7)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202133(US9233983, I-4)
Affinity DataIC50:  2nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202222(US9233983, R-1)
Affinity DataIC50:  2.20nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174202(US9102637, 237)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50237689(CHEMBL4066943)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of [3H]AVP binding to recombinant human vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202202(US9233983, P-17)
Affinity DataIC50:  2.5nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174160(US9102637, 195)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50237692(CHEMBL4091162)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of [3H]AVP binding to recombinant human vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174186(US9102637, 221)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174150(US9102637, 185)
Affinity DataIC50:  2.70nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM202218(US9233983, Q-1)
Affinity DataIC50:  2.90nMAssay Description:The inhibition assays were performed using the generic tyrosine kinase assay kit from C is Bio (HTRF KinEASE-TK #62TK0PEB). The assay is based on t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174196(US9102637, 231)
Affinity DataIC50:  2.90nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM174173(US9102637, 208)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The kinase assays were conducted in a 20 μl volume using 384-well plates (Greiner). The reaction mixture consists of compound or vehicle (1% DMS...More data for this Ligand-Target Pair
In DepthDetails US Patent
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