TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00230nM ΔG°: -69.1kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00550nM ΔG°: -66.9kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00680nM ΔG°: -66.3kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of MAP2K7 (unknown origin) using JNK peptide KFMMTPYVVTR incubated for 30 mins measured by multimode reader based ADP-glo assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of MAP2K7 (unknown origin) using JNK peptide KFMMTPYVVTR incubated for 30 mins measured by multimode reader based ADP-glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Binding affinity determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Binding affinity determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Binding affinity determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membrane was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membrane was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Binding affinity of the compound was determined against ETA receptor in porcine aortic smooth muscle membrane was determinedMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DatapH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair