TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Compound was evaluated for the affinity towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was evaluated for the inhibitory constant of human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was evaluated for the affinity towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Compound was evaluated for the inhibitory constant of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 8.5nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Compound was evaluated for the affinity towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 18nM ΔG°: -46.0kJ/molepH: 5.5 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity against recombinant thymidylate synthase in E. coliMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibitory effect against recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Agouron Pharmaceuticals
Curated by ChEMBL
Agouron Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Inhibition of recombinant human Glycinamide Ribonucleotide Transformylase (GART) using N10-formyl-5,8-dideazafolate (FDDF) as the cofactor .More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 33nM ΔG°: -44.4kJ/molepH: 5.5 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity against recombinant thymidylate synthase in E. coliMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity against recombinant thymidylate synthase in E. coliMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity against recombinant thymidylate synthase in E. coliMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Binding affinity against HIV -1 proteaseMore data for this Ligand-Target Pair