Compile Data Set for Download or QSAR
maximum 50k data
Found 45 with Last Name = 'weinberger' and Initial = 'dr'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047726((4-Iodo-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-a...)
Affinity DataKi:  2nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000074(CHEMBL142596 | [2-(3-Chloro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000081(CHEMBL358109 | [2-(4-Chloro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047727(CHEMBL152057 | [2-(3-Iodo-phenyl)-ethyl]-methyl-(2...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047724(CHEMBL152426 | [2-(4-Iodo-phenyl)-ethyl]-methyl-(2...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047719(CHEMBL346153 | [2-(4-Bromo-phenyl)-ethyl]-methyl-(...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50010743(N,N'-Di-p-tolyl-guanidine)
Affinity DataKi:  3.10nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047725((3-Iodo-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-a...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047721(CHEMBL151136 | [2-(3-Bromo-phenyl)-ethyl]-methyl-(...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047728(CHEMBL152478 | [2-(3-Fluoro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047723(CHEMBL153758 | [2-(4-Fluoro-phenyl)-ethyl]-methyl-...)
Affinity DataKi:  6nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047720((3-Bromo-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50047722((2-Iodo-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-a...)
Affinity DataKi:  27nMAssay Description:Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- PentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467094(CHEMBL4281164)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467089(CHEMBL4295161)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082133(CHEMBL3422652)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467091(CHEMBL4287966)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082128(CHEMBL3422654)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082132(CHEMBL3422653)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467088(CHEMBL4280063)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082129(CHEMBL3421643)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467089(CHEMBL4295161)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082136(CHEMBL3422659)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082129(CHEMBL3421643)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082128(CHEMBL3422654)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082133(CHEMBL3422652)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467092(CHEMBL4284586)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467090(CHEMBL4279997)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082132(CHEMBL3422653)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467088(CHEMBL4280063)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467089(CHEMBL4295161)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082133(CHEMBL3422652)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082128(CHEMBL3422654)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082138(CHEMBL3422661)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArsenite methyltransferase(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467093(CHEMBL4295236)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AS3MT using NaAsO2 as substrate preincubated for 30 minutes followed by substrate addition measured after 90 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082132(CHEMBL3422653)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467092(CHEMBL4284586)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082129(CHEMBL3421643)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467094(CHEMBL4281164)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467092(CHEMBL4284586)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467088(CHEMBL4280063)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length DOT1L (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50467094(CHEMBL4281164)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full-length NSD2 (unknown origin) using HeLa oligonucleosome as substrate preincubated for 15 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed