Affinity DataIC50: 7nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in CHO cell membranes assessed as inhibition of RANTES-stimulated [35S]-GTPgammaS binding afte...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institute Of Pharmaceutical Industry
Curated by ChEMBL
Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]5HT reuptake at rat brain frontal cortex serotonin transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 136nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 159nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Inhibition of [3H]norepinephrine reuptake at rat brain frontal cortex norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
Affinity DataIC50: 202nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 238nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 247nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 252nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 291nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 325nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 328nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 338nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institute Of Pharmaceutical Industry
Curated by ChEMBL
Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of [3H]5HT reuptake at rat brain frontal cortex serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 357nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 363nMAssay Description:Inhibition of [3H]-DA uptake in human dopamine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 374nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Institute Of Pharmaceutical Industry
Curated by ChEMBL
Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 375nMAssay Description:Inhibition of [3H]5HT reuptake at rat brain frontal cortex serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 379nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 389nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 399nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 401nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 412nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 425nMAssay Description:Inhibition of [3H]norepinephrine reuptake at rat brain frontal cortex norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 425nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 426nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 428nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 449nMAssay Description:Inhibition of [3H]-serotonin uptake in human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 473nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in CHO cells assessed as inhibition of RANTES-induced intracellular Ca2+ mobilization after 10 mins by ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 478nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute Of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 495nMAssay Description:Inhibition of [3H]-NE uptake in human norepinephrine transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair