Compile Data Set for Download or QSAR
maximum 50k data
Found 62 with Last Name = 'widomski' and Initial = 'dl'
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284125(7-[3-(4-Isopropylcarbamoyl-3-methoxy-2-propyl-phen...)
Affinity DataIC50:  0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50213060(CHEMBL355401 | SC-50135)
Affinity DataIC50: <0.100nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284122(7-[3-(4-Dimethylcarbamoyl-3-methoxy-2-propyl-pheno...)
Affinity DataIC50:  0.150nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284123(7-[3-(3-Methoxy-4-methylcarbamoyl-2-propyl-phenoxy...)
Affinity DataIC50:  0.850nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50001610(7-[3-(4-Acetyl-3-methoxy-2-propyl-phenoxy)-propoxy...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM16016(CHEMBL437747 | N-cyclohexyl-4-[4-(3,4-dichlorophen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM16016(CHEMBL437747 | N-cyclohexyl-4-[4-(3,4-dichlorophen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033746(7-[3-(4-Carbamoyl-3-methoxy-2-propyl-phenoxy)-prop...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205246((S)-(-)-N-(1-(3-(2-(4-isopropoxyphenoxy)thiazol-5-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284121(7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcarbam...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50203981(CHEMBL376717 | N-(4-(2-(4-(cyclopropylmethoxy)phen...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205248(CHEMBL220271 | N-(1-(3-(2-(4-isopropoxyphenoxy)thi...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50284124(3-{(R)-7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methy...)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205245(1-(4-(2-(4-(cyclopropylmethoxy)phenoxy)thiazol-5-y...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50052017(3-{7-[3-(2-Cyclopropylmethyl-3-methoxy-4-methylcar...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205243(CHEMBL220321 | N-(4-(2-(3-chloro-4-(cyclopropylmet...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50037390(3-{(S)-2-(2-Carboxy-ethyl)-7-[3-(2-cyclopropylmeth...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15913(2-pyridinecarboxamide deriv. 8c | 4-Amino-5-cyano-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189630(CHEMBL377212 | N-(4-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205246((S)-(-)-N-(1-(3-(2-(4-isopropoxyphenoxy)thiazol-5-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194856(CHEMBL374269 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  23nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15918(2-pyridinecarboxamide deriv. 12 | 4-Amino-5-chloro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205249(CHEMBL222464 | methyl 4-(2-(4-(cyclopropylmethoxy)...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205247(CHEMBL219902 | N-(1-(2'-(4-isopropoxyphenoxy)-2,5'...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196993(4-amino-N-((4-chloropyridin-3-yl)methyl)-5-cyano-6...)
Affinity DataIC50:  30nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189615(1-(4-(2-(4-isopropoxyphenoxy)thiazol-5-yl)but-3-yn...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50013889((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity against leukotriene B4 receptorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196992((Z)-4-(3-(4-(3-(dimethylamino)propoxy)phenyl)-3-hy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189628((S)-(-)-{3-[2-(4-isopropoxy-phenoxy)-thiazol-4-yl]...)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205250(CHEMBL220825 | N-(4-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196997(CHEMBL240859 | N-(4-(phenylsulfinyl)benzyl)-4-amin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196994(4-amino-5-cyano-6-ethoxy-N-(2-(5-nitropyridin-2-yl...)
Affinity DataIC50:  61nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15918(2-pyridinecarboxamide deriv. 12 | 4-Amino-5-chloro...)
Affinity DataIC50:  74nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194908(CHEMBL219112 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  81nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205248(CHEMBL220271 | N-(1-(3-(2-(4-isopropoxyphenoxy)thi...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50194904(CHEMBL375795 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  96nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15913(2-pyridinecarboxamide deriv. 8c | 4-Amino-5-cyano-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196998(CHEMBL391502 | N-(4-(phenylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  130nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205247(CHEMBL219902 | N-(1-(2'-(4-isopropoxyphenoxy)-2,5'...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205244((R)-(+)-N-(1-(3-(2-(4-isopropoxyphenoxy)thiazol-5-...)
Affinity DataIC50:  630nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205249(CHEMBL222464 | methyl 4-(2-(4-(cyclopropylmethoxy)...)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50203981(CHEMBL376717 | N-(4-(2-(4-(cyclopropylmethoxy)phen...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50189616(CHEMBL210384 | N-(3-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205245(1-(4-(2-(4-(cyclopropylmethoxy)phenoxy)thiazol-5-y...)
Affinity DataIC50:  3.11E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205244((R)-(+)-N-(1-(3-(2-(4-isopropoxyphenoxy)thiazol-5-...)
Affinity DataIC50:  3.35E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205243(CHEMBL220321 | N-(4-(2-(3-chloro-4-(cyclopropylmet...)
Affinity DataIC50:  4.25E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50063300((L-N6-1-iminoethyl)lysine | (S)-6-Acetimidoylamino...)
Affinity DataIC50:  5.90E+3nMAssay Description:The concentration required for inhibition of Human inducible nitric oxide synthase (iNOS) isoformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196995(CHEMBL239785 | N-(4-(methylsulfonyl)benzyl)-4-amin...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50196996(CHEMBL391579 | N-(4-(methylsulfonyl)benzyl)-5-cyan...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202707(CHEMBL219842 | N-(3-(2-(4-isopropoxyphenoxy)thiazo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 62 total ) | Next | Last >>
Jump to: