Compile Data Set for Download or QSAR
maximum 50k data
Found 123 with Last Name = 'williams' and Initial = 'ej'
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293243(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50:  1nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50190001(CHEMBL213007 | N-(5-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  1nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50072961(CHEMBL3410672)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293242(CHEMBL497198 | N4-(5-chlorobenzo[d][1,3]dioxol-4-y...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293244(CHEMBL523744 | N-(3-(4-(5-chlorobenzo[d][1,3]dioxo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293247(CHEMBL468970 | N4-(5-chlorobenzo[d][1,3]dioxol-4-y...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189995(CHEMBL213874 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50190000(CHEMBL214798 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50190002(CHEMBL387265 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189993(2-(4-(4-(3-chloro-2-fluorophenylamino)-7-methoxyqu...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189990(CHEMBL215786 | N-(3-chloro-4-fluorophenyl)-7-metho...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189991(CHEMBL214857 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50179758(CHEMBL203725 | N-(3-chloro-4-fluorophenyl)-5-(1-me...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50072963(CHEMBL3410548)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189998(CHEMBL385471 | N-(5-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50190003(2-(4-(4-(5-chloro-2-fluorophenylamino)-7-methoxyqu...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50179766(CHEMBL205149 | N-(3-chloro-4-fluorophenyl)-7-metho...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189994(CHEMBL276154 | N-(3-chloro-4-fluorophenyl)-7-metho...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293240(CHEMBL523088 | N-(3-(4-(5-chlorobenzo[d][1,3]dioxo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293248(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50:  13nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293245(CHEMBL496968 | N,N'-(5-(4-(5-chlorobenzo[d][1,3]di...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293247(CHEMBL468970 | N4-(5-chlorobenzo[d][1,3]dioxol-4-y...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189992(CHEMBL385479 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  18nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50179760(CHEMBL203295 | N-(3-chloro-4-fluorophenyl)-7-metho...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  23nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293241(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50:  23nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384248(CHEMBL2030451)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant truncated FLAG-tagged mTOR (1362 to 2549 aa) (unknown origin) expressed in HEK293 cells using biotinylated p70 peptide as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293242(CHEMBL497198 | N4-(5-chlorobenzo[d][1,3]dioxol-4-y...)
Affinity DataIC50:  32nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50:  35nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25223(2,4-Pyrimidine derivative, 25 | 3-({4-[(5-chloro-2...)
Affinity DataIC50:  40nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25223(2,4-Pyrimidine derivative, 25 | 3-({4-[(5-chloro-2...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50:  43nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189997(CHEMBL384699 | N-(5-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  51nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50179757(CHEMBL205776 | N-(3-chloro-4-fluorophenyl)-7-(3-(4...)
Affinity DataIC50:  66nMAssay Description:Inhibitory activity against EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293249(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50:  77nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25226(2,4-Pyrimidine derivative, 28 | 4-N-(5-chloro-2H-1...)
Affinity DataIC50:  90nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25226(2,4-Pyrimidine derivative, 28 | 4-N-(5-chloro-2H-1...)
Affinity DataIC50:  90nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222490((R)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  97nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189999(CHEMBL214631 | N-(5-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  106nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293239(CHEMBL497194 | N2-(3,5-bis(methylsulfonyl)phenyl)-...)
Affinity DataIC50:  114nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50189996(CHEMBL215559 | N-(5-chloro-2-fluorophenyl)-7-metho...)
Affinity DataIC50:  114nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  131nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 123 total ) | Next | Last >>
Jump to: