Affinity DataKi: 900nM ΔG°: -35.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nM ΔG°: -34.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nM ΔG°: -33.5kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nM ΔG°: -32.2kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 5.40E+3nM ΔG°: -31.3kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 1.92E+4nM ΔG°: -28.0kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nM ΔG°: -27.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+4nM ΔG°: -25.8kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+4nM ΔG°: -25.2kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+5nM ΔG°: -22.9kJ/molepH: 7.0 T: 2°CAssay Description:AMACR activity was determined by monitoring the interconversion of the (25R/S)-isomer of THC-CoA. Reaction product was analyzed by resolution of (25S...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of full-length human GST-tagged MALT1 isoform A (824 residues) expressed in Escherichia coli using Ac-LRSR-MCA as substrate after 1 hr by ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent auto-ubiquitination in presence of ATP measured after 13 hrs by fluore...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of full-length human GST-tagged MALT1 isoform A (824 residues) expressed in Escherichia coli using Ac-LRSR-MCA as substrate after 1 hr by ...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 5.09E+4nMAssay Description:Inhibition of full-length human GST-tagged MALT1 isoform A (824 residues) expressed in Escherichia coli using Ac-LRSR-MCA as substrate after 1 hr by ...More data for this Ligand-Target Pair