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Found 64 with Last Name = 'witty' and Initial = 'mj'
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50357427(CHEMBL1917511)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP2D6-mediated dextromethorphan O-demethylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030836(CHEMBL3355639)
Affinity DataIC50:  400nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030835(CHEMBL3355638)
Affinity DataIC50:  400nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030836(CHEMBL3355639)
Affinity DataIC50:  400nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129589(CHEMBL3628223)
Affinity DataIC50:  500nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122024(CHEMBL3617454)
Affinity DataIC50:  700nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122022(CHEMBL3617353)
Affinity DataIC50:  900nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129559(CHEMBL3234071)
Affinity DataIC50:  900nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129562(CHEMBL3628220)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122020(CHEMBL3617330)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50357427(CHEMBL1917511)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP1A2-mediated phencetin o-de-ethylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496040(CHEMBL3120287)
Affinity DataIC50:  1.80E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496036(CHEMBL3120293)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50558661(CHEMBL4763231)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400228(CHEMBL2181495)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122023(CHEMBL3617452)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122019(CHEMBL3120274)
Affinity DataIC50:  2.70E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122019(CHEMBL3120274)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496037(CHEMBL3120280)
Affinity DataIC50:  2.80E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50385911(CHEMBL531475 | TCMDC-133351)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400227(CHEMBL2181489)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50385911(CHEMBL531475 | TCMDC-133351)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human ERG channel expressed in Chinese hamster lung cells after 6 to 7 mins by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50357427(CHEMBL1917511)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human ERG expressed in Chinese hamster CHL cells by perforated patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496198(CHEMBL3124985)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496197(CHEMBL3124981)
Affinity DataIC50: >3.70E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030837(CHEMBL3355624)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030832(CHEMBL3355629)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50385912(CHEMBL2041980)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50129560(CHEMBL3628216)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50558662(CHEMBL4763365)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400226(CHEMBL2181298)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50122025(CHEMBL3617456)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496039(CHEMBL3120281)
Affinity DataIC50:  6.80E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496202(CHEMBL3124980)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400225(CHEMBL2181490)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50496038(CHEMBL3120265)
Affinity DataIC50:  8.50E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400224(CHEMBL2181492)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50357427(CHEMBL1917511)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of CYP2C9-mediated Tolbutamide methlyhydroxylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50558663(CHEMBL4798032)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50558659(CHEMBL4530341)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400223(CHEMBL2181497)
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400230(CHEMBL2181481)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400231(CHEMBL2181496)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400232(CHEMBL2181493)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400229(CHEMBL2181487)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50030833(CHEMBL3355633)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50357427(CHEMBL1917511)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP2C19-mediated (S)-mephenytoin 4'-hydroxylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400236(CHEMBL2181296)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400235(CHEMBL2181297)
Affinity DataIC50:  1.97E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM50400234(CHEMBL2181488)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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