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Found 422 with Last Name = 'wynne' and Initial = 'gm'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102438(US8536158, B)
Affinity DataKi:  1nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102440(US8536158, D)
Affinity DataKi:  1nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102436(US8536158, 2)
Affinity DataKi:  2nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102435(US8536158, 1)
Affinity DataKi:  2nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102437(US8536158, 3)
Affinity DataKi:  7nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM50397646(CHEMBL2181804 | US8536158, A)
Affinity DataKi:  7nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040934(CHEMBL3353833)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040901(CHEMBL3353822)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040944(CHEMBL3354395)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040934(CHEMBL3353833)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040891(CHEMBL3353812)
Affinity DataKi:  155nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040935(CHEMBL3353834)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040948(CHEMBL3354399)
Affinity DataKi:  235nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102441(US8536158, E)
Affinity DataKi:  258nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040935(CHEMBL3353834)
Affinity DataKi:  275nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040936(CHEMBL3353835)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040947(CHEMBL3354398)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040943(CHEMBL3353842)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040880(CHEMBL3353802)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040945(CHEMBL3354396)
Affinity DataKi:  360nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040952(CHEMBL3354403)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040956(CHEMBL3354407)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040955(CHEMBL3354406)
Affinity DataKi:  490nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102439(US8536158, C)
Affinity DataKi:  979nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040901(CHEMBL3353822)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040947(CHEMBL3354398)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040955(CHEMBL3354406)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040945(CHEMBL3354396)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040891(CHEMBL3353812)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040880(CHEMBL3353802)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040956(CHEMBL3354407)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040948(CHEMBL3354399)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040936(CHEMBL3353835)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040944(CHEMBL3354395)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040943(CHEMBL3353842)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50040952(CHEMBL3354403)
Affinity DataKi: >6.00E+4nMAssay Description:Displacement of [3H]CP55940 from human CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50:  0.00600nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50:  0.00900nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552190(CHEMBL4741714)
Affinity DataIC50:  0.0180nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50387298(CHEMBL2048872)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PIM1 using full-length BAD as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552189(CHEMBL4793492)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human PIM1 using full length BAD peptide substrate in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50248903(CHEMBL4060012)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552189(CHEMBL4793492)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human PIM3 using full length BAD peptide substrate in presence of ATP at Km concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50387298(CHEMBL2048872)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human PIM3 using full-length BAD as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50248920(CHEMBL4079975)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50248897(CHEMBL4061984)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50248893(CHEMBL4104431)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50248921(CHEMBL4096030)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50552147(CHEMBL4794742)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of PIM1 (unknown origin) by coupled kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50436459(CHEMBL2396661)
Affinity DataIC50:  5nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
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