Affinity DataKi: 1nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity to 5-HT7 in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of 4-[18F]fluoro-N-[4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide from mGluR1 in Sprague-Dawley rat brain hom...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 9.70nMAssay Description:Binding affinity to 5-HT7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Displacement of 4-[18F]fluoro-N-[4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide from mGluR1 in Sprague-Dawley rat brain hom...More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 13.6nMAssay Description:Displacement of [18F]FITM from mGlu1 receptor in rat brain homogenates after 1 hr by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 22.2nMAssay Description:Displacement of [18F]FITM from mGlu1 receptor in rat brain homogenates after 1 hr by gamma countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 27.3nMAssay Description:Displacement of [18F]FITM from mGlu1 receptor in rat brain homogenates after 1 hr by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 116nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 138nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
National Institute Of Radiological Sciences
Curated by ChEMBL
National Institute Of Radiological Sciences
Curated by ChEMBL
Affinity DataKi: 153nMAssay Description:Displacement of 4-[18F]fluoro-N-[4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl]-N-methylbenzamide from mGluR1 in Sprague-Dawley rat brain hom...More data for this Ligand-Target Pair
Affinity DataKi: 164nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 192nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 193nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 194nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 203nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 218nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 226nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 278nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 312nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 323nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 328nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 374nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair