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Found 256 with Last Name = 'yahiaoui' and Initial = 's'
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079375(CHEMBL3417008 | US9663465, 20)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558239(CHEMBL4781228)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079377(CHEMBL3417007)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079367(CHEMBL3416998)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079365(CHEMBL3416996 | US9663465, 8)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558245(CHEMBL4789661)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079366(CHEMBL3416997 | US9663465, 12)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079369(CHEMBL3417000 | US9663465, 11)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558234(CHEMBL4780536)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558243(CHEMBL4746550)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558238(CHEMBL4741579)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558241(CHEMBL4760149)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079368(CHEMBL3416999 | US9663465, 16)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558235(CHEMBL4799043)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079364(CHEMBL3416995 | US9663465, 7)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM84950(CAS_183782 | NSC_183782 | RS 67333)
Affinity DataKi:  9.30nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558248(CHEMBL4751840)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558247(CHEMBL4749344)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079363(CHEMBL3414597 | US9663465, 6)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558242(CHEMBL4799839)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558246(CHEMBL4795251)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558240(CHEMBL4786794)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079371(CHEMBL3417002)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079372(CHEMBL3417003)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558236(CHEMBL4793078)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558237(CHEMBL4788022)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558249(CHEMBL4748287)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips) - Helmholtz Centre For Infection Research (Hzi

Curated by ChEMBL
LigandPNGBDBM50542712(CHEMBL4647152)
Affinity DataKi:  41nMAssay Description:Inhibition of Pseudomonas aeruginosa LasB using aminobenzoyl-Ala-Gly-Leu-Ala-p-nitro-benzyl-amide as fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50558244(CHEMBL4751353)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-GR113808 from guinea pig brain 5HT4 receptor in presence of serotonin incubated for 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079376(CHEMBL3417005)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079374(CHEMBL3417006)
Affinity DataKi:  122nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558235(CHEMBL4799043)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells in presence of serotonin incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558237(CHEMBL4788022)
Affinity DataKi:  147nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells in presence of serotonin incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558236(CHEMBL4793078)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells in presence of serotonin incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558234(CHEMBL4780536)
Affinity DataKi:  160nMAssay Description:Displacement of [125I]+/-DOI from human recombinant 5-HT2C receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079373(CHEMBL3417004)
Affinity DataKi:  193nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558234(CHEMBL4780536)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells in presence of serotonin incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558234(CHEMBL4780536)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]ketanserin human recombinant 5-HT2A receptor after 60 mins by scintillation counting analysis relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Normandie Universit£

Curated by ChEMBL
LigandPNGBDBM50558238(CHEMBL4741579)
Affinity DataKi:  834nMAssay Description:Displacement of [3H]-LSD from human 5-HT6 receptor expressed in HEK293 cells in presence of serotonin incubated for 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079362(CHEMBL3417009 | US9663465, 9)
Affinity DataIC50:  16nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips) - Helmholtz Centre For Infection Research (Hzi

Curated by ChEMBL
LigandPNGBDBM50542711(CHEMBL4640494)
Affinity DataIC50:  17nMAssay Description:Inhibition of Clostridium histolyticum ColH peptidase domain expressed in Escherichia coli BL21(DE3) cells using Mca-Ala-Gly-Pro-Pro-Gly-Pro-Dpa-Gly-...More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  18nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase [1-48](Homo sapiens (Human))
BiomolÉCules Et Cibles Cellulaires Tumorales

LigandPNGBDBM13061(4,4 -(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitr...)
Affinity DataIC50:  18nMAssay Description:The inhibitory activities of the compounds toward aromatase were determined in vitro using human placental microsomes and [1,2,6,7-3H]-androstenedion...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Cermn

Curated by ChEMBL
LigandPNGBDBM50079373(CHEMBL3417004)
Affinity DataIC50:  24nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50345191(7,8-Benzo-4'-hydroxy-4-imidazolylflavan | CHEMBL17...)
Affinity DataIC50:  32nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50345190(2,4-cis-7,8-benzo-4'-cyano-4-imidazolylflavan | 2,...)
Affinity DataIC50:  34nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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