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Found 38 with Last Name = 'yan' and Initial = 'xe'
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ERBB4 cytoplasmic domain (708 to 993 residues) expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of full-length recombinant human His-tagged BLK expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant human IgG1 Fc-tagged ERBB2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234190(CHEMBL4079861)
Affinity DataIC50:  24nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  25nMAssay Description:Inhibition of full-length recombinant human His-tagged BTK cytoplasmic domain expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234176(CHEMBL4087740)
Affinity DataIC50:  26nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234177(CHEMBL4105621)
Affinity DataIC50:  33nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234188(CHEMBL4083486)
Affinity DataIC50:  37nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234183(CHEMBL4086000)
Affinity DataIC50:  47nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234179(CHEMBL4095439)
Affinity DataIC50:  57nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234180(CHEMBL4103194)
Affinity DataIC50:  66nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234181(CHEMBL4078914)
Affinity DataIC50:  97nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234185(CHEMBL4072048)
Affinity DataIC50:  97nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  111nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50462213(CHEMBL4247298)
Affinity DataIC50:  132nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using poly(4:1 Glu,Tyr) peptide as substrate preincubated for 1 hr followed by addition of ATP and measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataIC50:  161nMAssay Description:Inhibition of full-length recombinant human His-tagged MEK1 expressed in baculovirus by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234182(CHEMBL4064475)
Affinity DataIC50:  166nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234195(CHEMBL4091276)
Affinity DataIC50:  169nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234193(CHEMBL4068047)
Affinity DataIC50:  182nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234189(CHEMBL4078120)
Affinity DataIC50:  208nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50131841(CHEMBL3633143)
Affinity DataIC50:  330nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM149404(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)
Affinity DataIC50:  344nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234194(CHEMBL4082515)
Affinity DataIC50:  445nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234197(CHEMBL4102389)
Affinity DataIC50:  472nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234184(CHEMBL4063421)
Affinity DataIC50:  550nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234187(CHEMBL4093766)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234191(CHEMBL4097883)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234186(CHEMBL4099008)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234192(CHEMBL4073062)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50234196(CHEMBL4101484)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of N-terminal 6His/TEV protease cleavage site-tagged wild type human EGFR using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50462213(CHEMBL4247298)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of DDR1 (unknown origin) using poly(4:1 Glu,Tyr) peptide as substrate preincubated for 1 hr followed by addition of ATP and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50462213(CHEMBL4247298)
Affinity DataIC50:  6.12E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly(4:1 Glu,Tyr) peptide as substrate preincubated for 1 hr followed by addition of ATP and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50462213(CHEMBL4247298)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ABL1 (unknown origin) using poly(4:1 Glu,Tyr) peptide as substrate preincubated for 1 hr followed by addition of ATP and measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50462213(CHEMBL4247298)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of c-KIT (unknown origin) using poly(4:1 Glu,Tyr) peptide as substrate preincubated for 1 hr followed by addition of ATP and measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50054654(CHEMBL4068839)
Affinity DataEC50:  70nMAssay Description:Inhibition of wild-type EGFR (unknown origin) autophosphorylation at Y1068 expressed in mouse BAF3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataEC50:  43nMAssay Description:Inhibition of wild-type EGFR (unknown origin) autophosphorylation at Y1068 expressed in mouse BAF3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair