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Found 897 with Last Name = 'yao' and Initial = 'h'
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092959(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092961(1-(isopropylsulfonyl)-4-(4-(1-(4-(4-methoxyphenyls...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092969(CHEMBL74117 | Cyclopropyl-(4-{1-[4-(4-methoxy-benz...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092958(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)p...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092962(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092968(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.350nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092974(1'-Benzenesulfonyl-4-{1-[4-(4-methoxy-benzenesulfo...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092965(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092960(1'-(Butane-1-sulfonyl)-4-{1-[4-(4-methoxy-benzenes...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50604668(CHEMBL5180947)
Affinity DataKi:  0.400nMAssay Description:Mixed-type inhibition of AChE in mouse cerebral cortex using acetylthiocholine iodide as substrate by double reciprocal Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092973(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092963(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092970(1'-Ethanesulfonyl-4-{1-[4-(4-methoxy-benzenesulfon...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092972(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092964(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  0.991nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092957(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)-1-(...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092966(1-(benzylsulfonyl)-4-(4-(1-(4-(4-methoxyphenylsulf...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117910(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity at endothelin receptor subtype AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092971(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092975(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  3nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092967(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092959(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125977(CHEMBL3627897)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human factor 9a using CH3SO2-DCHG-Gly-Arg-AFC.AcOH as substrate preinubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092957(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)-1-(...)
Affinity DataKi:  9.10nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092968(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  9.80nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092962(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  10nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117910(4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)
Affinity DataKi:  10nMAssay Description:Binding affinity at type 1 angiotensin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50151405(CHEMBL3775211 | US10189819, Example 79)
Affinity DataKi:  11nMAssay Description:Inhibition of human factor 9a using CH3SO2-DCHG-Gly-Arg-AFC.AcOH as substrate preinubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092963(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  11nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092973(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  15nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092958(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)vinyl)p...)
Affinity DataKi:  26nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092961(1-(isopropylsulfonyl)-4-(4-(1-(4-(4-methoxyphenyls...)
Affinity DataKi:  32nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092966(1-(benzylsulfonyl)-4-(4-(1-(4-(4-methoxyphenylsulf...)
Affinity DataKi:  33nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092974(1'-Benzenesulfonyl-4-{1-[4-(4-methoxy-benzenesulfo...)
Affinity DataKi:  37nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092972(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  41nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092965(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  42nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092960(1'-(Butane-1-sulfonyl)-4-{1-[4-(4-methoxy-benzenes...)
Affinity DataKi:  57nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092964(4-{1-[4-(4-Methoxy-benzenesulfonyl)-phenyl]-vinyl}...)
Affinity DataKi:  60nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092967(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  61nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092969(CHEMBL74117 | Cyclopropyl-(4-{1-[4-(4-methoxy-benz...)
Affinity DataKi:  68nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092970(1'-Ethanesulfonyl-4-{1-[4-(4-methoxy-benzenesulfon...)
Affinity DataKi:  74nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092975(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  96nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171301((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  110nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Shanghai Jiao Tong University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50092971(1-(4-(4-(1-(4-(4-methoxyphenylsulfonyl)phenyl)viny...)
Affinity DataKi:  117nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382173(CHEMBL2022157)
Affinity DataKi:  145nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in HEK293 cells by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382173(CHEMBL2022157)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in HEK293 cells by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382170(CHEMBL2022154)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in HEK293 cells by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50382170(CHEMBL2022154)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in HEK293 cells by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50171302((S)-(2-{3-[((9S,12S)-12-Cyclohexyl-11,14-dioxo-2-o...)
Affinity DataKi:  160nMAssay Description:Ability to inhibit the hydrolysis of chromogenic 4-phenylazophenyl ester from the peptide fragment Ac- DTEDVVP(Nva)-O-4-PAP in a HCV protease continu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50347133(CHEMBL1439099)
Affinity DataKi:  256nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor expressed in HEK293 cells by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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