Found 370 with Last Name = 'yau' and Initial = 'mk' TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Displacement of [3H]2-furoyl-LIGRL-NH2 from human PAR2 expressed in human NCTC-2544 cells by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Antagonist at C3a receptor in human LAD2 cells assessed as inhibition of C3a-induced beta-hexosaminidase release preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-C3a from human C3aR expressed in rat RBL-2H3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human PAR2 expressed in human A549 cells assessed as inhibition of 2f-LIGRLO-NH2-induced NFkappaB activation by luciferase rep...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human PAR2 expressed in human A549 cells coexpressing TACR1 assessed as inhibition of substance P-induced IL-8 production by E...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]-C3a from C3aR in human MDM cells after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Antagonist activity at C3a receptor in human MDM cells assessed as inhibition of C3a-induced intracellular calcium release preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting methodMore data for this Ligand-Target Pair
